• Anti-sea lice agents in Norwegian aquaculture; surveillance, treatment trends and possible implications for food safety 

      Hannisdal, Rita; Nøstbakken, Ole Jakob; Hove, Helge Torbjørn; Madsen, Lise; Horsberg, Tor Einar; Lunestad, Bjørn Tore (Peer reviewed; Journal article, 2020)
      Sea lice are a major challenge for the Norwegian aquaculture, and to cope with sea lice infections, several physical, biological and chemical treatments are applied. This study presents data on the use of anti-sea lice ...
    • A catalog of microbial genes from the bovine rumen unveils a specialized and diverse biomass-degrading environment 

      Li, Junhua; Zhong, Huanzi; Ramayo-Caldas, Yuliaxis; Terrapon, Nicolas; Lombard, Vincent; Potocki-Veronese, Gabrielle; Estellé, Jordi; Popova, Milka; Yang, Ziyi; Zhang, Hui; Li, Fang; Tang, Shanmei; Yang, Fangming; Chen, Weineng; Chen, Bing; Li, Jiyang; Guo, Jing; Martin, Cécile; Maguin, Emmanuelle; Xu, Xun; Yang, Huanming; Wang, Jian; Madsen, Lise; Kristiansen, Karsten; Henrissat, Bernard; Ehrlich, Stanislav D; Morgavi, Diego P (Peer reviewed; Journal article, 2020)
      Background The rumen microbiota provides essential services to its host and, through its role in ruminant production, contributes to human nutrition and food security. A thorough knowledge of the genetic potential of rumen ...
    • Commercially available kelp and seaweed products – valuable iodine source or risk of excess intake? 

      Aakre, Inger; Solli, Dina Doblaug; Markhus, Maria Wik; Mæhre, Hanne K; Dahl, Lisbeth; Henjum, Sigrun; Alexander, Jan; Korneliussen, Patrick-Andre; Madsen, Lise; Kjellevold, Marian (Peer reviewed; Journal article, 2021)
      Background: Seaweeds and kelps, also known as macroalgae, have long been common in the East-Asian diet. During recent years, macroalgae have entered the global food market, and a variety of macroalgae products are now ...
    • CRISPR/cascade 9-mediated genome editing-challenges and opportunities 

      Roy, Bhaskar; Zhao, Jing; Yang, Chao; Luo, Wen; Xiong, Teng; Li, Yong; Fang, Xiaodong; Gao, Guanjun; Singh, Chabungbam O; Madsen, Lise; Zhou, Yong; Kristiansen, Karsten (Journal article; Peer reviewed, 2018)
      Clustered Regularly Interspaced Palindromic Repeats (CRISPR) and Cascade 9 (also known as Cas9, CRISPR associated protein 9) confer protection against invading viruses or plasmids. The CRISPR/Cascade 9 system constitutes ...
    • Dietary Proteins, Brown Fat, and Adiposity 

      Madsen, Lise; Myrmel, Lene Secher; Fjære, Even; Øyen, Jannike; Kristiansen, Karsten (Journal article; Peer reviewed, 2018)
      High protein diets have become popular for body weight maintenance and weight loss despite controversies regarding efficacy and safety. Although both weight gain and weight loss are determined by energy consumption and ...
    • Distinct gut metagenomics and metaproteomics signatures in prediabetics and treatment-naive type 2 diabetics 

      Zhong, Huanzi; Ren, Huahui; Lu, Yan; Fang, Chao; Hou, Guixue; Yang, Ziyi; Chen, Bing; Yang, Fangming; Zhao, Yue; Shi, Zhun; Zhou, Baojin; Wu, Jiegen; Zou, Hua; Zi, Jin; Chen, Jiayu; Bao, Xiao; Hu, Yihe; Gao, Yan; Zhang, Jun; Xu, Xun; Hou, Yong; Yang, Huanming; Wang, Jian; Liu, Siqi; Jia, Huijue; Madsen, Lise; Brix, Susanne; Kristiansen, Karsten; Liu, Fang; Li, Junhua (Peer reviewed; Journal article, 2019)
      Background The gut microbiota plays important roles in modulating host metabolism. Previous studies have demonstrated differences in the gut microbiome of T2D and prediabetic individuals compared to healthy individuals, ...
    • Effects of exercise and dietary protein sources on adiposity and insulin sensitivity in obese mice 

      Fjære, Even; Myrmel, Lene Secher; Lützhøft, Ditte Olsen; Andersen, Hanne; Holm, Jacob Bak; Kiilerich, Pia; Hannisdal, Rita; Liaset, Bjørn; Kristiansen, Karsten; Madsen, Lise (Journal article; Peer reviewed, 2019)
      Low-fat diets and exercise are generally assumed to ameliorate obesity-related metabolic dysfunctions, but the importance of exercise vs. dietary changes is debated. Male C57BL/6J mice were fed a high-fat/high-sucrose ...
    • Effects of frozen storage on phospholipid content in atlantic cod fillets and the influence on diet-induced obesity in mice 

      Fauske, Kristin Røen; Bernhard, Annette; Fjære, Even; Myrmel, Lene Secher; Frøyland, Livar; Kristiansen, Karsten; Liaset, Bjørn; Madsen, Lise (Peer reviewed; Journal article, 2018)
    • Effects of geography and species variation on selenium and mercury molar ratios in Northeast Atlantic marine fish communities 

      Mahjour Azad, Atabak; Frantzen, Sylvia; Bank, Michael; Nilsen, Bente Merete; Duinker, Arne; Madsen, Lise; Måge, Amund (Journal article; Peer reviewed, 2019)
      Methylmercury (MeHg) is a potent neurotoxin that bioaccumulates in seafood. Co-occurrence of selenium (Se) may affect the bioavailability and toxicity of MeHg in organisms. Here we report the concentrations of total mercury ...
    • Factors influencing risk assessments of brominated flame-retardants; evidence based on seafood from the North East Atlantic Ocean 

      Nøstbakken, Ole Jakob; Duinker, Arne; Rasinger, Josef Daniel; Nilsen, Bente Merete; Sanden, Monica; Frantzen, Sylvia; Hove, Helge Torbjørn; Lundebye, Anne-Katrine; Berntssen, Marc; Hannisdal, Rita; Madsen, Lise; Måge, Amund (Journal article; Peer reviewed, 2018)
      Brominated flame-retardants (BFRs) such as polybrominated diphenyl ethers (PBDE) and hexabromocyclododecane (HBCD) are considered hazardous to human health. Due to their persistence, they are still present in the environment ...
    • Fish-derived proteins and their potential to improve human health 

      Dale, Hanna Fjeldheim; Madsen, Lise; Lied, Gülen Arslan (Journal article; Peer reviewed, 2019)
      Emerging evidence from studies evaluating the effect of lean fish consumption in humans suggests that proteins from fish have several beneficial metabolic effects. Rest, or waste, material from the fishing industry contains ...
    • Iodine status and thyroid function in a group of seaweed consumers in Norway 

      Aakre, Inger; Evensen, Lidunn Tveito; Kjellevold, Marian; Dahl, Lisbeth; Henjum, Sigrun; Alexander, Jan; Madsen, Lise; Markhus, Maria Wik (Peer reviewed; Journal article, 2020)
      Seaweeds, or macroalgae, may be a good dietary iodine source but also a source of excessive iodine intake. The main aim in this study was to describe the iodine status and thyroid function in a group of macroalgae consumers. ...
    • Lean-seafood intake increases urinary iodine concentrations and plasma selenium levels: a randomized controlled trial with crossover design 

      Øyen, Jannike; Aadland, Eli Kristin; Liaset, Bjørn; Fjære, Even; Dahl, Lisbeth; Madsen, Lise (Peer reviewed; Journal article, 2020)
      Iodine deficiency due to insufficient nutritional intake is a public health challenge in several European countries, including Norway. Lean-seafood has a high iodine and arsenic (As) content and is a good source of selenium ...
    • Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism 

      Jensen, Benjamin Anderschou Holbech; Holm, Jacob B.; Larsen, Ida S.; von Burg, Nicole; Derer, Stefanie; Sonne, Si B.; Pærrgaard, Simone I.; Damgaard, Mads V.; Indrelid, Stine Hufthammer; Rivollier, Aymeric; Agrinier, Anne-Laure; Sulek, Karolina; Arnoldussen, Yke Jildouw; Fjære, Even; Marette, André; Angell, Inga Leena; Rudi, Knut; Treebak, Jonas Thue; Madsen, Lise; Åkesson, Caroline Piercey; Agace, William; Sina, Christian; Kleiveland, Charlotte Ramstad; Kristiansen, Karsten; Lea, Tor Erling (Peer reviewed; Journal article, 2021)
      Interactions between host and gut microbial communities are modulated by diets and play pivotal roles in immunological homeostasis and health. We show that exchanging the protein source in a high fat, high sugar, westernized ...
    • Mercury bioaccumulation pathways in tusk (Brosme brosme) from Sognefjord, Norway: Insights from C and N isotopes 

      Mahjour Azad, Atabak; Frantzen, Sylvia; Bank, Michael; Madsen, Lise; Måge, Amund (Peer reviewed; Journal article, 2020)
      Seafood is the main source of methylmercury (MeHg) exposure for humans and elevated total mercury (Hg) concentrations have been reported in marine fish from Norwegian fjords compared with offshore areas. Hg in tusk fillets ...
    • Metagenome-wide association of gut microbiome features for schizophrenia 

      Zhu, Feng; Ju, Yanmei; Wang, Wei; Wang, Qi; Guo, Ruijin; Ma, Qingyan; Sun, Qiang; Fan, Yajuan; Xie, Yuying; Yang, Zai; Jie, Zhuye; Zhao, Binbin; Xiao, Liang; Yang, Lin; Zhang, Tao; Feng, Junqin; Guo, Liyang; He, Xiaoyan; Chen, Yunchun; Chen, Ce; Gao, Chengge; Xu, Xun; Yang, Huanming; Wang, Jian; Dang, Yonghui; Madsen, Lise; Brix, Susanne; Kristiansen, Karsten; Jia, Huijue; Ma, Xiancang (Peer reviewed; Journal article, 2020)
      Evidence is mounting that the gut-brain axis plays an important role in mental diseases fueling mechanistic investigations to provide a basis for future targeted interventions. However, shotgun metagenomic data from ...
    • Monitoring Program for Pharmaceuticals, illegal substances and contaminants in farmed fish - Annual report for 2019 

      Bernhard, Annette; Nøstbakken, Ole Jakob; Frøyland, Livar; Madsen, Lise; Hannisdal, Rita (Rapport fra havforskningen;2020 - 26, Research report, 2020)
      This report summarises the monitoring data collected in 2019 on the status of illegal substances, pharmaceuticals and contaminants in Norwegian farmed fish. A total of 13 725 fish were collected. Samples examined for illegal ...
    • Monitoring program for pharmaceuticals, illegal substances, and contaminants in farmed fish - annual report for 2017 

      Hannisdal, Rita; Nøstbakken, Ole Jakob; Lunestad, Bjørn Tore; Hove, Helge Torbjørn; Frøyland, Livar; Madsen, Lise (Rapport fra havforskningen;27-2018, Research report, 2018)
      This report summarises the monitoring data collected in 2017 on the status of illegal substances, pharmaceuticals and contaminants in Norwegian farmed fish. A total of 13 640 fish were collected, of these almost 40% were ...
    • Monitoring program for pharmaceuticals, illegal substances, and contaminants in farmed fish - Annual report for 2018 

      Hannisdal, Rita; Bernhard, Annette; Nøstbakken, Ole Jakob; Lunestad, Bjørn Tore; Frøyland, Livar; Madsen, Lise (Rapport fra havforskningen;2019 - 44, Research report, 2019)
      This report summarises the monitoring data collected in 2018 on the status of illegal substances, pharmaceuticals and contaminants in Norwegian farmed fish. A total of 13 920 fish were collected. Samples examined for illegal ...
    • One-Year Treatment with Olanzapine Depot in Female Rats: Metabolic Effects 

      Ersland, Kari Merete; Myrmel, Lene Secher; Fjære, Even; Berge, Rolf Kristian; Madsen, Lise; Steen, Vidar Martin; Skrede, Silje (Journal article; Peer reviewed, 2019)
      Background Antipsychotic drugs can negatively affect the metabolic status of patients, with olanzapine as one of the most potent drugs. While patients are often medicated for long time periods, experiments in rats typically ...