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dc.contributor.authorMathisen, Gro Haarklou
dc.contributor.authorAlexander, Jan
dc.contributor.authorFæste, Christiane Kruse
dc.contributor.authorHusøy, Trine
dc.contributor.authorKnutsen, Helle Katrine
dc.contributor.authorØrnsrud, Robin
dc.contributor.authorSteffensen, Inger-Lise
dc.date.accessioned2020-10-14T11:43:10Z
dc.date.available2020-10-14T11:43:10Z
dc.date.created2020-08-01T12:45:44Z
dc.date.issued2020
dc.identifier.citationFood Research International. 2020, 137:109499 1-13.en_US
dc.identifier.issn0963-9969
dc.identifier.urihttps://hdl.handle.net/11250/2682801
dc.description.abstractChemical contaminants are present in all foods. Data on the occurrence of contaminants in foods that are often consumed or contain high contaminant concentrations are critical for the estimation of exposure and evaluation of potential negative health effects. Due to limited resources for the monitoring of contaminants and other chemical substances in foods, methods for prioritisation are needed. We have developed a straightforward semi-quantitative method to rank chemical substances in foods for monitoring as part of a risk-based food control. The method is based on considerations of toxicity, level of exposure including both occurrence in food and dietary intake, vulnerability of one or more population groups due to high exposure because of special food habits or resulting from specific genetic variants, diseases, drug use or age/life stages, and the adequacy of both toxicity and exposure data. The chemical substances ranked for monitoring were contaminants occurring naturally, unintentionally or incidentally in foods or formed during food processing, and the inclusion criteria were high toxicity, high exposure and/or lack of toxicity or exposure data. In principle, this method can be used for all classes of chemical substances that occur in foods, both unintended contaminants and deliberately added chemical substances. Foods considered relevant for monitoring of the different chemical substances were also identified. The outcomes of ranking exercises using the new method including considerations of vulnerable groups and adequacy of data and a shortened version based on risk considerations only were compared. The results showed that the resolution between the contaminants was notably increased with the extended method, which we considered as advantageous for the ranking of chemical substances for monitoring in foods.en_US
dc.language.isoengen_US
dc.titleA ranking method of chemical substances in foods for prioritisation of monitoring, based on health risk and knowledge gapsen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.source.pagenumber1-13en_US
dc.source.volume137:109499en_US
dc.source.journalFood Research Internationalen_US
dc.identifier.doi10.1016/j.foodres.2020.109499
dc.identifier.cristin1821177
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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