Vis enkel innførsel

dc.contributor.authorDjurdjevic, Ida
dc.contributor.authorFurmanek, Tomasz
dc.contributor.authorMiyazawa, Seita
dc.contributor.authorSusnik Bajec, Simona
dc.date.accessioned2020-01-24T09:38:44Z
dc.date.available2020-01-24T09:38:44Z
dc.date.created2019-09-12T17:59:35Z
dc.date.issued2019
dc.identifier.citationBMC Genomics. 2019, 20 (1), 1-15.nb_NO
dc.identifier.issn1471-2164
dc.identifier.urihttp://hdl.handle.net/11250/2637764
dc.description.abstractBackground Enormous variability in skin colour and patterning is a characteristic of teleost fish, including Salmonidae fishes, which present themselves as a suitable model for studying mechanisms of pigment patterning. In order to screen for candidate genes potentially involved in the specific skin pigment pattern in marble trout (labyrinthine skin pattern) and brown trout (spotted skin pattern), we conducted comparative transcriptome analysis between differently pigmented dermis sections of the adult skin of the two species. Results Differentially expressed genes (DEGs) possibly associated with skin pigment pattern were identified. The expression profile of 27 DEGs was further tested with quantitative real-time PCR on a larger number of samples. Expression of a subset of ten of these genes was analysed in hybrid (marble x brown) trout individuals and compared with the complexity of their skin pigment pattern. A correlation between the phenotype and the expression profile assessed for hybrid individuals was detected for four (gja5, clcn2, cdkn1a and tjp1) of the ten candidate genes tested. The potential role of these genes in skin pigment pattern maintenance is discussed. Conclusions Our results indicate that the maintenance of different pigment patterns in trout is dependent upon specific communication—involving gap junctions, tight junctions and ion channels—between chromatophores present in differentially pigmented skin regions.nb_NO
dc.language.isoengnb_NO
dc.titleComparative transcriptome analysis of trout skin pigment cellsnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionpublishedVersionnb_NO
dc.source.pagenumber1-15nb_NO
dc.source.volume20nb_NO
dc.source.journalBMC Genomicsnb_NO
dc.source.issue1nb_NO
dc.identifier.doi10.1186/s12864-019-5714-1
dc.identifier.cristin1724165
cristin.unitcode7431,24,0,0
cristin.unitnameReproduksjon og utvikl.biologi
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel