Browsing Brage IMR by Author "Rasinger, Josef"
Now showing items 1-20 of 24
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Benefit and risk assessment of fish in the Norwegian diet - Scientific Opinion of the Steering Committee of the Norwegian Scientific Committee for Food and Environment
Andersen, Lene Frost; Berstad, Paula; Bukhvalova, Barbara Alexandra; Carlsen, Monica Hauger; Dahl, Lisbeth Jane; Goksøyr, Anders; Sletting Jakobsen, Lea; Knutsen, Helle Katrine; Kvestad, Ingrid; Lillegaard, Inger Therese Laugsand; Mangschou, Bente; Meyer, Haakon Eduard; Parr, Christine Louise; Rakkestad, Kirsten Eline; Rasinger, Josef; Sengupta, Sayantan; Skeie, Guri; Starrfelt, Jostein; Ulven, Stine Marie (Peer reviewed; Journal article, 2022) -
Benefit and risk assessment of fish in the Norwegian diet - Scientific Opinion of the Steering Committee of the Norwegian Scientific Committee for Food and Environment
Andersen, Lene Frost; Berstad, Paula; Bukhvalova, Barbara Alexandra; Carlsen, Monica Hauger; Dahl, Lisbeth Jane; Goksøyr, Anders; Jakobsen, Lea Sletting; Knutsen, Helle Katrine; Kvestad, Ingrid; Lillegaard, Inger Therese Laugsand; Mangschou, Bente; Meyer, Haakon Eduard; Parr, Christine Louise; Rakkestad, Kirsten Eline; Rasinger, Josef; Sengupta, Sayantan; Skeie, Guri; Starrfelt, Jostein; Ulven, Stine Marie; Agdestein, Angelika; Bodin, Johanna Eva; Bruzell, Ellen Merete; Elvevoll, Edel O.; Hemre, Gro Ingunn; Hessen, Dag Olav; Husøy, Trine; Krogdahl, Åshild; Nilsen, Asbjørn Magne; Skjerdal, Olaug Taran; Steffensen, Inger-Lise; Strand, Tor Arne; Vandvik, Vigdis; Velle, Gaute; Wasteson, Yngvild; Alexander, Jan (Peer reviewed; Journal article, 2022) -
Co-exposure to UV radiation and crude oil increases acute embryotoxicity and sublethal malformations in the early life stages of Atlantic haddock (Melanogrammus aeglefinus)
Sørhus, Elin; Donald, Carey; Nakken, Charlotte L.; Perrichon, Prescilla; Durif, Caroline; Shema, Steven; Browman, Howard; Skiftesvik, Anne Berit; Lie, Kai Kristoffer; Rasinger, Josef; Müller, Mette Helen Bjørge; Meier, Sonnich (Peer reviewed; Journal article, 2023)Crude oil causes severe abnormalities in developing fish. Photomodification of constituents in crude oil increases its toxicity several fold. We report on the effect of crude oil, in combination with ultraviolet (UV) ... -
CompareMS2 2.0: An Improved Software for Comparing Tandem Mass Spectrometry Datasets
Marissen, Rob; Varunjikar, Madhushri Shrikant; Laros, Jeroen F. J.; Rasinger, Josef; Neely, Benjamin A.; Palmblad, Magnus (Peer reviewed; Journal article, 2022)It has long been known that biological species can be identified from mass spectrometry data alone. Ten years ago, we described a method and software tool, compareMS2, for calculating a distance between sets of tandem mass ... -
Comparing novel shotgun DNA sequencing and state-of-the-art proteomics approaches for authentication of fish species in mixed samples
Varunjikar, Madhushri S.; Moreno-Ibarguen, Carlos; Andrade-Martinez, Juan S.; Tung, Hui-Shan; Belghit, Ikram; Palmblad, Magnus; Olsvik, Pål Asgeir; Reyes, Alejandro; Rasinger, Josef; Lie, Kai Kristoffer (Others, 2021)Replacement of high-value fish species with cheaper varieties or mislabelling of food unfit for human consumption is a global problem violating both consumers’ rights and safety. For distinguishing fish species in pure ... -
Crude oil exposure of early life stages of Atlantic haddock suggests threshold levels for developmental toxicity as low as 0.1 μg total polyaromatic hydrocarbon (TPAH)/L
Sørhus, Elin; Sørensen, Lisbet; Grøsvik, Bjørn Einar; Le Goff, Jérémie; Incardona, John P.; Linbo, Tiffany; Baldwin, David; Karlsen, Ørjan; Nordtug, Trond; Hansen, Bjørn Henrik; Thorsen, Anders; Donald, Carey; van der Meeren, Terje; Robson, William; Rowland, Steven J.; Rasinger, Josef; Vikebø, Frode Bendiksen; Meier, Sonnich (Peer reviewed; Journal article, 2023)Atlantic haddock (Melanogrammus aeglefinus) embryos bind dispersed crude oil droplets to the eggshell and are consequently highly susceptible to toxicity from spilled oil. We established thresholds for developmental toxicity ... -
Developing a framework for open and FAIR data management practices for next generation risk- and benefit assessment of fish and seafood
Pineda-Pampliega, Javier; Bernhard, Annette; Hannisdal, Rita; Ørnsrud, Robin; Mathisen, Gro Haarklou; Solstad, Gisle; Rasinger, Josef (Peer reviewed; Journal article, 2022)Risk and risk–benefit assessments of food are complex exercises, in which access to and use of several disconnected individual stand-alone databases is required to obtain hazard and exposure information. Data obtained from ... -
Dietary selenomethionine reduce mercury tissue levels and modulate methylmercury induced proteomic and transcriptomic alterations in hippocampi of adolescent BALB/c mice
Mellingen, Ragnhild Marie; Myrmel, Lene Secher; Rasinger, Josef; Lie, Kai Kristoffer; Bernhard, Annette; Madsen, Lise; Nøstbakken, Ole Jakob (Peer reviewed; Journal article, 2022)Methylmercury (MeHg) is a well-known environmental contaminant, particularly harmful to the developing brain. The main human dietary exposure to MeHg occurs through seafood consumption. However, seafood also contains several ... -
Future feed control – Tracing banned bovine material in insect meal
Belghit, Ikram; Varunjikar, Madhushri Shrikant; Lecrenier, Marie-Caroline; Steinhilber, A.; Niedzwiecka, A.; Wang, Y.V.; Dieu, Marc; Azzollini, D.; Lie, Kai Kristoffer; Lock, Erik Jan Robert; Berntssen, Marc HG; Renard, Patricia; Zagon, Jutta; Fumière, Olivier; van Loon, Loon; Larsen, Thomas; Poetz, O.; Braeuning, Albert; Palmblad, Magnus; Rasinger, Josef (Peer reviewed; Journal article, 2021)In the present study, we assessed if different legacy and novel molecular analyses approaches can detect and trace prohibited bovine material in insects reared to produce processed animal protein (PAP). Newly hatched black ... -
Hepatotoxic pyrrolizidine alkaloids induce DNA damage response in rat liver in a 28-day feeding study
Ebmeyer, Johanna; Rasinger, Josef; Hengstler, Jan G.; Schaudien, Dirk; Creutzenberg, Otto; Lampen, Alfonso; Braeuning, Albert; Hassel-Pras, Stefanie (Peer reviewed; Journal article, 2020)Pyrrolizidine alkaloids (PA) are secondary plant metabolites that occur as food and feed contaminants. Acute and subacute PA poisoning can lead to severe liver damage in humans and animals, comprising liver pain, hepatomegaly ... -
Mapping of nutrients, food additives and contaminants in plant-based and gluten-free food products and their meat, dairy and gluten-containing counterparts
Devold, Tove Gulbrandsen; Andreassen, Monica; Carlsen, Monica Hauger; Denison, Eva Marie-Louise; Mathisen, Gro Haarklou; Rasinger, Josef; Svendsen, Camilla; Bruzell, Ellen Merete; Granum, Berit Brunstad; Husøy, Trine (Peer reviewed; Journal article, 2023) -
Multi-tissue proteogenomic analysis for mechanistic toxicology studies in non-model species
Lin, M.S.; Varunjikar, Madhushri Shrikant; Lie, Kai Kristoffer; Søfteland, Liv Ingeborg Rosvoll; Dellafiora, L.; Ørnsrud, Robin; Sanden, Monica; Berntssen, Marc HG; Dorne, J.L.C.M.; Bafna, V.; Rasinger, Josef (Peer reviewed; Journal article, 2023)New approach methodologies (NAM), including omics and in vitro approaches, are contributing to the implementation of 3R (reduction, refinement and replacement) strategies in regulatory science and risk assessment. In this ... -
Proteomic analysis of hepatic effects of phenobarbital in mice with humanized liver
Sprenger, Heike; Rasinger, Josef; Hammer, Helen; Naboulsi, Wael; Zabinsky, Elke; Planatscher, Hannes; Schwarz, Michael; Poetz, Oliver; Braeuning, Albert (Peer reviewed; Journal article, 2022)Activation of the constitutive androstane receptor (CAR) may induce adaptive but also adverse effects in rodent liver, including the induction of drug-metabolizing enzymes, transient hepatocellular proliferation, and ... -
Pyrrolizidine alkaloid-induced transcriptomic changes in rat lungs in a 28-day subacute feeding study
Buchmueller, Julia; Sprenger, Heike; Ebmeyer, Johanna; Rasinger, Josef; Creutzenberg, Otto; Schaudien, Dirk; Hengstler, Jan G.; Guenther, Georgia; Braeuning, Albert; Hessel-Pras, Stefanie (Peer reviewed; Journal article, 2021)Pyrrolizidine alkaloids (PAs) are secondary plant metabolites synthesized by a wide range of plants as protection against herbivores. These toxins are found worldwide and pose a threat to human health. PAs induce acute ... -
Refined mackerel oil increases hepatic lipid accumulation and reduces choline and choline-containing metabolites in the liver tissue in mice fed a Western diet
Fjære, Even; Myrmel, Lene Secher; Rasinger, Josef; Bernhard, Annette; Frøyland, Livar; Madsen, Lise (Peer reviewed; Journal article, 2023)In this study, we aimed to evaluate the impact of consuming refined mackerel oil (MO) from rest raw material on hepatic fat accumulation, glucose tolerance, and metabolomic changes in the liver from male C57BL/6N mice. The ... -
Risk-benefit assessment of sunscreen - Opinion of the Panel on Food Additives, Flavourings, Processing Aids, Materials in Contact with Food, and Cosmetics of the Norwegian Scientific Committee for Food and Environment
Bruzell, Ellen Merete; Carlsen, Monica Hauger; Caspersen, Ida Henriette; Denison, Eva Marie-Louise; Devold, Tove Gulbrandsen; Granum, Berit Brunstad; Mathisen, Gro Haarklou; Rundén-Pran, Elise; Rasinger, Josef; Rohloff, Jens; Svendsen, Camilla; Husøy, Trine (Peer reviewed; Journal article, 2022)VKM has performed a risk-benefit assessment of sunscreen use and six UV filters. This task was undertaken on the initiative of a VKM Panel in response to the apparent paradox between the need for protective measures, such ... -
Risk-benefit assessment of sunscreen: Opinion of the Panel on Food Additives, Flavourings, Processing Aids, Materials in Contact with Food, and Cosmetics of the Norwegian Scientific Committee for Food and Environment
Bruzell, Ellen; Carlsen, Monica Hauger; Caspersen, Ida Henriette; Denison, Eva Marie-Louise; Devold, Tove Gulbrandsen; Granum, Berit; Mathisen, Gro Haarklou; Pran, Elise Rundén; Rasinger, Josef; Rohloff, Jens; Svendsen, Camilla; Husøy, Trine (Peer reviewed; Journal article, 2022) -
RNA sequencing and proteomic profiling reveal different alterations by dietary methylmercury in the hippocampal transcriptome and proteome in BALB/c mice
Mellingen, Ragnhild Marie; Myrmel, Lene Secher; Lie, Kai Kristoffer; Rasinger, Josef; Madsen, Lise; Nøstbakken, Ole Jakob (Peer reviewed; Journal article, 2021)Methylmercury (MeHg) is a highly neurotoxic form of mercury (Hg) present in seafood. Here, we recorded and compared proteomic and transcriptomic changes in hippocampus of male BALB/c mice exposed to two doses of MeHg. Mice ... -
Scoping review of research on gastrointestinal effects of selected emulsifiers, stabilisers, and thickeners
Denison, Eva Marie-Louise; Andreassen, Monica; Ellen M., Bruzell; Carlsen, Monica Hauger; Devold, Tove Gulbrandsen; Granum, Berit Brunstad; Mathisen, Gro Haarklou; Svendsen, Camilla; Rasinger, Josef; Husøy, Trine (Peer reviewed; Journal article, 2023) -
Seasonal variations in mercury, cadmium, lead and arsenic species in Norwegian blue mussels (Mytilus edulis L.) – Assessing the influence of biological and environmental factors
Gomez Delgado, Ana Isabel; Tibon, Jojo; Silva, Marta Sofia; Lundebye, Anne-Katrine; Aguera, Antonio; Rasinger, Josef; Strohmeier, Tore; Sele, Veronika (Peer reviewed; Journal article, 2023)Blue mussels (Mytilus edulis L.) can accumulate undesirable substances, including the potentially toxic elements (PTEs) cadmium (Cd), mercury, (Hg), lead (Pb), arsenic (As) and As species. In this study, the levels of PTEs ...