Blar i Brage IMR på forfatter "Holen, Elisabeth"
-
Choline supplementation increased total body lipid gain, while surplus methionine improved growth and amino acid retention in adult Atlantic salmon (Salmo salar)
Espe, Marit; Andersen, Synne Marte; Veiseth-Kent, Eva; Rønnestad, Ivar; Holen, Elisabeth; Zerrahn, Jens-Erik; Aksnes, Anders (Peer reviewed; Journal article, 2017)Methionine–choline-deficient (MCD) mammals are known to accumulate liver TAG probably due to phosphatidylcholine (PC) deficiency and thus assembly of VLDL and transport of lipids from liver to peripheral organs. To assess ... -
Development of a fatty liver model using oleic acid in primary liver cells isolated from Atlantic salmon and the prevention of lipid accumulation using metformin
Espe, Marit; Xie, Shiwei; Chen, Shijun; Araujo, Pedro; Holen, Elisabeth (Journal article; Peer reviewed, 2019)The following study aimed to develop a fatty liver model in primary hepatocytes isolated from Atlantic salmon. In order to induce the fatty liver, oleic acid (OA) at 0.2 or 0.4 mM was used. Metformin, known to prevent and ... -
Dietary chlorpyrifos-methyl exposure impair transcription of immune-, detoxification- and redox signaling genes in leukocytes isolated from cod (Gadus morhua)
Holen, Elisabeth; Espe, Marit; Larsen, Anett Kristin; Olsvik, Pål Asgeir (Peer reviewed; Journal article, 2022)Inclusion of new environmental toxicants increase with the amount of plant ingredients substituting marine proteins and oils in feed for farmed Atlantic salmon (Salma salar). Agricultural pesticides like chlorpyrifos-methyl, ... -
Dietary electrolyte balance of Atlantic salmon (Salmo salar) freshwater feeds: Impact on osmoregulation, mineral metabolism and performance in seawater
Prabhu, P. Antony Jesu; Fjelldal, Per Gunnar; Remø, Sofie C.; Selvam, Chandrasekar; Hamre, Kristin; Espe, Marit; Holen, Elisabeth; Skjærven, Kaja Helvik; Vikså, Vibeke; Subramanian, Saravanan; Schrama, Johan W.; Sissener, Nini (Peer reviewed; Journal article, 2022)Dietary electrolyte balance is the equilibrium of monovalent cations and anions that influence the acid-base balance of the feed (dEB = Na + K − Cl, mEq kg−1). Dietary electrolytes/minerals can influence the physiological ... -
Dietary selenium required to achieve body homeostasis and attenuate pro-inflammatory responses in Atlantic salmon post-smolt exceeds the present EU legal limit
Prabhu, P. Antony Jesu; Holen, Elisabeth; Espe, Marit; Silva, Marta Sofia; Holme, May-Helen; Hamre, Kristin; Lock, Erik-Jan; Waagbø, Rune (Peer reviewed; Journal article, 2020)Selenium (Se) supplementation either as inorganic or organic form was evaluated in Atlantic salmon post-smolt in vivo and in vitro. The basal diet was formulated to be low in fish meal and contain 0.24 mg Se kg−1; six other ... -
Differential production of prostaglandins and prostacyclins by liver and head kidney cells from Atlantic salmon challenged with arachidonic and eicosapentaenoic acids
Araujo, Hernandez Pedro W; Espe, Marit; Lucena, Eva; Yang, Yang; Holen, Elisabeth (Peer reviewed; Journal article, 2021)Polyunsaturated fatty acids such as arachidonic and eicosapentaenoic acids are the precursors of eicosanoid metabolites (e.g prostaglandins and prostacyclins) which regulate inflammatory and immune response processes in ... -
Leucine did not stimulate growth and accretion in either stressed or unstressed Atlantic salmon
Espe, Marit; Lai, Floriana; Gomes, Ana S.; De Santis, Christian; Hartviksen, Mali B.; Holen, Elisabeth; Rønnestad, Ivar (Peer reviewed; Journal article, 2021)The aim of the current trial was to test whether leucine affected growth and accretion including test any effects on leucine upon stress. Quadruplicate tanks each containing 50 Atlantic salmon (Salmo salar) (mean start ... -
Optimization of the Balance between Protein, Lipid and Carbohydrate in Diets for Lumpfish (Cyclopterus lumpus)
Hamre, Kristin; Berge, Gerd Marit; Sæle, Øystein; Holen, Elisabeth; Kousoulaki, Katerina; Remø, Sofie Charlotte; Krogdahl, Åshild; Lein, Ingrid (Peer reviewed; Journal article, 2022)The aim of this study was to investigate how the dietary balance between protein, lipid, and carbohydrate affects growth, welfare, and health with focus on immune responses, in lumpfish of body weight ranges 1.7-10 g and ... -
RNA form baker's yeast cultured with and without lipopolysaccharide (LPS) modulates gene transcription in an intestinal epithelial cell model, RTgutGC from rainbow trout (Oncorhynchus mykiss)
Holen, Elisabeth; Austgulen, Maren Hoff; Espe, Marit (Peer reviewed; Journal article, 2021)The objective of this study was to evaluate if the intestinal RTgutGC cell line could be suitable for research on dietary ingredients and their function as modulators of inflammation during lipopolysaccharide (LPS) induced stress. -
The effect of omega-3 and omega-6 polyunsaturated fatty acids on the production of cyclooxygenase and lipoxygenase metabolites by human umbilical vein endothelial cells
Araujo, Pedro; Belghit, Ikram; Aarsaether, Niels; Espe, Marit; Lucena, Eva; Holen, Elisabeth (Journal article; Peer reviewed, 2019)Although the correlation between polyunsaturated fatty acids (PUFA) and the production of pro- and anti-inflammatory metabolites is well documented, little is known about the simultaneous effect of different PUFA on the ... -
Trenger laks fettsyren EPA for optimal immunrespons? Rapport FHF prosjekt EPA-laks
Liland, Nina Sylvia; Sissener, Nini; Østbye, Tone-Kari K; Gjøen, Tor; Bou, Marta; Holen, Elisabeth; Ruyter, Bente Synnøve; Krasnov, Aleksei; Lutfi, Esmail; Espe, Marit; Stubhaug, Ingunn; Rosenlund, Grethe (Research report, 2021)Innhold av de langkjedede omega-3 fettsyrene i dietter blir ofte oppgitt som sum EPA + DHA, uten å ta spesielt hensyn til ratioen mellom de to fettsyrene. Laksens behov for DHA er velstudert. EPA omgjøres i stor grad til ... -
Validation of a Liquid–Liquid Extraction Method to Study the Temporal Production of D-Series Resolvins by Head Kidney Cells from Atlantic Salmon (Salmon salar) Exposed to Docosahexaenoic Acid
Araujo, Pedro; Iqbal, Sarah; Arnø, Aleksander; Espe, Marit; Holen, Elisabeth (Peer reviewed; Journal article, 2023)A simple and rapid method for the extraction of D-series resolvins (RvD1, RvD2, RvD3, RvD4, RvD5) released into Leibovitz’s L-15 complete medium by head kidney cells from Atlantic salmon and the further determination of ...