Blar i Brage IMR på forfatter "Fjære, Even"
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Adipose MDM2 regulates systemic insulin sensitivity
Hallenborg, Philip; Jensen, Benjamin Anderschou Holbech; Fjære, Even; Petersen, Rasmus Koefoed; Belmaâti, Mohammed-Samir; Rasmussen, Sarah Søndergård; Gunnarsson, Jon Petur; Lauritzen, Pernille; Cheng, Kenneth King Yip; Hermansson, Martin; Sonne, Si Brask; Ejsing, Christer S.; Xu, Aimin; Kratchmarova, Irina; Krüger, Marcus; Madsen, Lise; Kristiansen, Karsten; Blagoev, Blagoy (Peer reviewed; Journal article, 2021)The intimate association between obesity and type II diabetes urges for a deeper understanding of adipocyte function. We and others have previously delineated a role for the tumor suppressor p53 in adipocyte biology. Here, ... -
Bioavailability of iodine from a meal consisting of sushi and a wakame seaweed salad—A randomized crossover trial
Aakre, Inger; Tveit, Inger Beate; Myrmel, Lene Secher; Fjære, Even; Ballance, Simon; Rosendahl-Riise, Hanne (Peer reviewed; Journal article, 2023)The consumption of seaweed is on the rise in the Western world. Seaweeds may contain substantial amounts of iodine, and some species could serve as a potential dietary iodine source. However, limited data on the iodine ... -
Dietary Proteins, Brown Fat, and Adiposity
Madsen, Lise; Myrmel, Lene Secher; Fjære, Even; Øyen, Jannike; Kristiansen, Karsten (Journal article; Peer reviewed, 2018)High protein diets have become popular for body weight maintenance and weight loss despite controversies regarding efficacy and safety. Although both weight gain and weight loss are determined by energy consumption and ... -
Effects of exercise and dietary protein sources on adiposity and insulin sensitivity in obese mice
Fjære, Even; Myrmel, Lene Secher; Lützhøft, Ditte Olsen; Andersen, Hanne; Holm, Jacob Bak; Kiilerich, Pia; Hannisdal, Rita; Liaset, Bjørn; Kristiansen, Karsten; Madsen, Lise (Journal article; Peer reviewed, 2019)Low-fat diets and exercise are generally assumed to ameliorate obesity-related metabolic dysfunctions, but the importance of exercise vs. dietary changes is debated. Male C57BL/6J mice were fed a high-fat/high-sucrose ... -
Effects of frozen storage on phospholipid content in atlantic cod fillets and the influence on diet-induced obesity in mice
Fauske, Kristin Røen; Bernhard, Annette; Fjære, Even; Myrmel, Lene Secher; Frøyland, Livar; Kristiansen, Karsten; Liaset, Bjørn; Madsen, Lise (Peer reviewed; Journal article, 2018) -
Intake of different types of seafood and meat and risk of type 2 diabetes in women: a prospective study supported by a dietary intervention in mice
Myrmel, Lene Secher; Øyen, Jannike; Brantsæter, Anne Lise; Fjære, Even; Haugvaldstad, Karen; Birkeland, Kåre Inge; Nygård, Ottar Kjell; Kristiansen, Karstein Berge; Egeland, Grace M.; Madsen, Lise (Peer reviewed; Journal article, 2024)Detailed knowledge regarding the associations between intake of different types of seafood and meat and the risk of type 2 diabetes (T2D), and insight into possible mechanisms are warranted. In this study we aimed to ... -
Iodine Bioavailability and Accumulation of Arsenic and Cadmium in Rats Fed Sugar Kelp (Saccharina latissima)
Fjære, Even; Poulsen, Rikke; Duinker, Arne; Liaset, Bjørn; Hansen, Martin; Madsen, Lise; Myrmel, Lene Secher (Peer reviewed; Journal article, 2022)Suboptimal iodine status is a prominent public health issue in several European coun-tries. Brown algae have a high iodine content that, upon intake, may exceed the recommended dietary intake level, but iodine bioavailability ... -
Knowledge update on macroalgae food and feed safety - based on data generated in the period 2014-2019 by the Institute of Marine Research, Norway
Duinker, Arne; Kleppe, Malin; Fjære, Even; Biancarosa, Irene; Heldal, Hilde Elise; Dahl, Lisbeth; Lunestad, Bjørn Tore (Rapport fra havforskningen;2020 - 44, Research report, 2020)It has previously been addressed that some species of macroalgae may contain elevated levels of iodine, cadmium and inorganic arsenic. With the increased amount of data in the present report it is now possible to discriminate ... -
Lean-seafood intake increases urinary iodine concentrations and plasma selenium levels: a randomized controlled trial with crossover design
Øyen, Jannike; Aadland, Eli Kristin; Liaset, Bjørn; Fjære, Even; Dahl, Lisbeth; Madsen, Lise (Peer reviewed; Journal article, 2020)Iodine deficiency due to insufficient nutritional intake is a public health challenge in several European countries, including Norway. Lean-seafood has a high iodine and arsenic (As) content and is a good source of selenium ... -
Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism
Jensen, Benjamin Anderschou Holbech; Holm, Jacob B.; Larsen, Ida S.; von Burg, Nicole; Derer, Stefanie; Sonne, Si B.; Pærrgaard, Simone I.; Damgaard, Mads V.; Indrelid, Stine Hufthammer; Rivollier, Aymeric; Agrinier, Anne-Laure; Sulek, Karolina; Arnoldussen, Yke Jildouw; Fjære, Even; Marette, André; Angell, Inga Leena; Rudi, Knut; Treebak, Jonas Thue; Madsen, Lise; Åkesson, Caroline Piercey; Agace, William; Sina, Christian; Kleiveland, Charlotte Ramstad; Kristiansen, Karsten; Lea, Tor Erling (Peer reviewed; Journal article, 2021)Interactions between host and gut microbial communities are modulated by diets and play pivotal roles in immunological homeostasis and health. We show that exchanging the protein source in a high fat, high sugar, westernized ... -
Metabolic effects of diet containing blue mussel (Mytilus edulis) and blue mussel-fed salmon in a mouse model of obesity
Mahjour Azad, Atabak; Bernhard, Annette; Shen, Anne; Myrmel, Lene Secher; Lundebye, Anne-Katrine; Lecaudey, Laurene Alicia; Fjære, Even; Ho, Quang Tri; Sveier, Harald; Kristiansen, Karsten; Limborg, Morten Tønsberg; Madsen, Lise (Peer reviewed; Journal article, 2023)Alternative feed ingredients for farmed salmon are warranted due to increasing pressure on wild fish stocks. As locally farmed blue mussels may represent an environmentally sustainable substitute with a lower carbon ... -
One-Year Treatment with Olanzapine Depot in Female Rats: Metabolic Effects
Ersland, Kari Merete; Myrmel, Lene Secher; Fjære, Even; Berge, Rolf Kristian; Madsen, Lise; Steen, Vidar Martin; Skrede, Silje (Journal article; Peer reviewed, 2019)Background Antipsychotic drugs can negatively affect the metabolic status of patients, with olanzapine as one of the most potent drugs. While patients are often medicated for long time periods, experiments in rats typically ... -
Overexpression of cyclooxygenase-2 in adipocytes reduces fat accumulation in inguinal white adipose tissue and hepatic steatosis in high-fat fed mice
Danneskiold-Samsø, Niels Banhos; Sonne, Si Brask; Larsen, Jeppe Madura; Ann Normann, Hansen; Fjære, Even; Isidor, Marie Sophie; Petersen, Sidsel; Henningsen, Jeanette; Severi, Ilenia; Sartini, Loris; Schober, Yvonne; Wolf, Jacqueline; Nockher, W. Andreas; Wolfrum, Christian; Cinti, Saverio; Sina, Christian; Hansen, Jacob B.; Madsen, Lise; Brix, Susanne; Kristiansen, Karsten (Journal article; Peer reviewed, 2019)Cyclooxygenases are known as important regulators of metabolism and immune processes via conversion of C20 fatty acids into various regulatory lipid mediators, and cyclooxygenase activity has been implicated in browning ... -
Refined mackerel oil increases hepatic lipid accumulation and reduces choline and choline-containing metabolites in the liver tissue in mice fed a Western diet
Fjære, Even; Myrmel, Lene Secher; Rasinger, Josef; Bernhard, Annette; Frøyland, Livar; Madsen, Lise (Peer reviewed; Journal article, 2023)In this study, we aimed to evaluate the impact of consuming refined mackerel oil (MO) from rest raw material on hepatic fat accumulation, glucose tolerance, and metabolomic changes in the liver from male C57BL/6N mice. The ... -
The anti-obesogenic effect of lean fish species is influenced by the fatty acid composition in fish fillets
Fjære, Even; Myrmel, Lene Secher; Dybing, Karianne; Kuda, Ondrej; Jensen, Benjamin Anderschou Holbech; Rossmeisl, Martin; Frøyland, Livar; Kristiansen, Karsten; Madsen, Lise (Peer reviewed; Journal article, 2020) -
The impact of different animal-derived protein sources on adiposity and glucose homeostasis during ad libitum feeding and energy restriction in already obese mice
Myrmel, Lene Secher; Fauske, Kristin Røen; Fjære, Even; Bernhard, Annette; Liisberg, Ulrike; Hasselberg, Astrid Elise; Øyen, Jannike; Kristiansen, Karsten; Madsen, Lise (Journal article; Peer reviewed, 2019)Low-fat diets and energy restriction are recommended to prevent obesity and to induce weight loss, but high-protein diets are popular alternatives. However, the importance of the protein source in obesity prevention and ...