Blar i Brage IMR på forfatter "Yadetie, Fekadu"
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Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars)
Söderström, Sofie Karin; Lille-Langøy, Roger; Yadetie, Fekadu; Rauch, Mateusz; Milinski, Ana; Dejaegere, Annick; Stote, Roland H.; Goksøyr, Anders; Karlsen, Odd André (Peer reviewed; Journal article, 2022)Toxicity mediated by per- and polyfluoroalkyl substances (PFAS), and especially perfluoroalkyl acids (PFAAs), has been linked to activation of peroxisome proliferator-activated receptors (Ppar) in many vertebrates. Here, ... -
Bioaccumulation of mercury and transcriptional responses in tusk (Brosme brosme), a deep-water fish from a Norwegian fjord
Olsvik, Pål Asgeir; Mahjour Azad, Atabak; Yadetie, Fekadu (Peer reviewed; Journal article, 2021)High concentrations of mercury (Hg) have been documented in deep-water fish species from some Norwegian fjords. In this study, tusk (Brosme brosme) was sampled from four locations in the innermost parts of Sognefjorden in ... -
Effects of Agricultural Pesticides in Aquafeeds on Wild Fish Feeding on Leftover Pellets Near Fish Farms
Olsvik, Pål Asgeir; Larsen, Anett Kristin; Berntssen, Marc; Goksøyr, Anders; Karlsen, Odd Andre; Yadetie, Fekadu; Sanden, Monica; Kristensen, Torstein (Others, 2019)Screening has revealed that modern-day feeds used in Atlantic salmon aquaculture might contain trace amounts of agricultural pesticides. To reach slaughter size, salmon are produced in open net pens in the sea. Uneaten ... -
Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms
Olsvik, Pål Asgeir; Larsen, Anett Kristin; Berntssen, Marc; Goksøyr, Anders; Karlsen, Odd Andre; Yadetie, Fekadu; Sanden, Monica; Kristensen, Torstein (Journal article; Peer reviewed, 2019)Screening has revealed that modern-day feeds used in Atlantic salmon aquaculture might contain trace amounts of agricultural pesticides. To reach slaughter size, salmon are produced in open net pens in the sea. Uneaten ... -
Environmentally realistic concentrations of chlorinated, brominated, and fluorinated persistent organic pollutants induce the unfolded protein response as a shared stress pathway in the liver of Atlantic cod (Gadus morhua)
Olsvik, Pål Asgeir; Meier, Sonnich; Zhang, Xiaokang; Goksøyr, Anders; Karlsen, Odd André; Yadetie, Fekadu (Peer reviewed; Journal article, 2023)In the North Sea and North Atlantic coastal areas, fish experience relatively high background levels of persistent organic pollutants. This study aimed to compare the mode of action of environmentally relevant concentrations ... -
Integrative omics-analysis of lipid metabolism regulation by peroxisome proliferator-activated receptor a and b agonists in male Atlantic cod
Eide, Marta; Goksøyr, Anders; Yadetie, Fekadu; Gilabert, Alejandra; Bartosova, Zdenka; Frøysa, Håvard Guldbrandsen; Fallahi, Shirin; Zhang, Xiaokang; Blaser, Nello; Jonassen, Inge; Bruheim, Per; Alendal, Guttorm; Brun, Morten; Porte, Cinta; Karlsen, Odd André (Peer reviewed; Journal article, 2023)Lipid metabolism is essential in maintaining energy homeostasis in multicellular organisms. In vertebrates, the peroxisome proliferator-activated receptors (PPARs, NR1C) regulate the expression of many genes involved in ... -
Intestinal permeability and gene expression after polyethylene and polyamide microplastic ingestion in Wistar rats.
Toto, Benuarda; Refosco, Alice; O'Keeffe, Maria; Barkhald, Øyvind Halås; Brønstad, Aurora Margrethe; Lied, Gülen Arslan; Yadetie, Fekadu; Goksøyr, Anders; Kögel, Tanja; Dierkes, Jutta (Peer reviewed; Journal article, 2022) -
Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua)
Aranguren Abadía, Libe; Yadetie, Fekadu; Donald, Carey; Sørhus, Elin; Myklatun, Lars Eirik; Zhang, Xiaokang; Lie, Kai Kristoffer; Perrichon, Prescilla; Nakken, Charlotte Langeland; Durif, Caroline; Shema, Steven; Browman, Howard; Skiftesvik, Anne Berit; Goksøyr, Anders; Meier, Sonnich; Karlsen, Odd André (Peer reviewed; Journal article, 2022)Photo-enhanced toxicity of crude oil is produced by exposure to ultraviolet (UV) radiation. Atlantic cod (Gadus morhua) embryos were exposed to crude oil with and without UV radiation (290–400 nm) from 3 days post fertilization ... -
Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua)
Dale, Karina; Yadetie, Fekadu; Müller, Mette Helen Bjørge; Pampanin, Daniela Maria; Gilabert, Alejandra; Zhang, Xiaokang; Tairova, Zhanna; Haarr, Ane; Lille-Langøy, Roger; Lyche, Jan Ludvig; Porte, Cinta; Karlsen, Odd Andre; Goksøyr, Anders (Peer reviewed; Journal article, 2020)The aim of the present study was to investigate effects of defined mixtures of polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs), at low, environmentally relevant (1× = L), or high (20× = H) ... -
ReCodLiver0.9: Overcoming Challenges in Genome-Scale Metabolic Reconstruction of a Non-model Species
Hanna, Eileen Marie; Zhang, Xiaokang; Eide, Marta; Fallahi, Shirin; Furmanek, Tomasz; Yadetie, Fekadu; Zielinski, Daniel Craig; Goksøyr, Anders; Jonassen, Inge (Peer reviewed; Journal article, 2020)The availability of genome sequences, annotations, and knowledge of the biochemistry underlying metabolic transformations has led to the generation of metabolic network reconstructions for a wide range of organisms in ... -
Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua)
Dale, Karina; Yadetie, Fekadu; Horvli, Torill; Zhang, Xiaokang; Frøysa, Håvard G; Karlsen, Odd André; Goksøyr, Anders (Peer reviewed; Journal article, 2022)The aim of the present study was to investigate effects of per- and polyfluoroalkyl substances (PFAS), both single compounds and a mixture of these, using precision-cut liver slices (PCLS) from Atlantic cod (Gadus morhua). ... -
Spawning time in adult polar cod (Boreogadus saida) altered by crude oil exposure, independent of food availability
Strople, Leah Catherine; Vieweg, Ireen; Yadetie, Fekadu; Odei, Derrick Kwame; Thorsen, Anders; Karlsen, Odd André; Goksøyr, Anders; Sørensen, Lisbet; Sarno, Antonio; Hansen, Bjørn Henrik; Frantzen, marianne; Hansen, Øyvind J; Puvanendran, Velmurugu; Nahrgang, Jasmine (Peer reviewed; Journal article, 2023)Fish early life stages are well known for their sensitivity to crude oil exposure. However, the effect of crude oil exposure on adults and their gametes during their spawning period is not well studied. Polar cod, a key ...