Browsing Brage IMR by Author "Whatmore, Paul"
Now showing items 1-12 of 12
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Acute stress response on Atlantic salmon: a time-course study of the effects on plasma metabolites, mucus cortisol levels, and head kidney transcriptome profile
Madaro, Angelico; Nilsson, Jonatan; Whatmore, Paul; Roh, HyeongJin; Grove, Søren; Stien, Lars Helge; Olsen, Rolf Erik (Peer reviewed; Journal article, 2022)Farmed Atlantic salmon (Salmo salar) welfare and performance can be strongly influenced by stress episodes caused by handling during farming practices. To better understand the changes occurring after an acute stress ... -
Associations Between Behavioral Effects of Bisphenol A and DNA Methylation in Zebrafish Embryos
Olsvik, Pål Asgeir; Whatmore, Paul; Penglase, Samuel; Skjærven, Kaja Helvik; Anglès d'Auriac, Marc; Ellingsen, Ståle (Peer reviewed; Journal article, 2019)Endocrine-disrupting contaminants have been associated with aberrant changes in epigenetic pathways in animals. In this study, zebrafish embryos were exposed bisphenol A (BPA) to search for associations between behavior ... -
Intestinal health in Atlantic salmon post-smolt (Salmo salar) when fed low- and high HUFA diets
Løvmo, Signe Dille; Sundh, Henrik; Whatmore, Paul; Nordvi, Malene Fosse; Sigholt, Trygve; Madaro, Angelico; Bardal, Tora; Olsen, Rolf Erik (Peer reviewed; Journal article, 2022)It is well established that farmed Atlantic salmon (Salmo salar) need n3-highly unsaturated fatty acids (HUFA) in their diet to thrive and grow. However, the biological functions to the individual HUFAs may differ, implying ... -
Low intestinal inflammation model (HP48) in Atlantic salmon (Salmo salar) and inflammatory mitigation by Bactocell
Nordvi, Malene Fosse; Løvmo, Signe Dille; Whatmore, Paul; Sundh, Henrik; Sigholt, Trygve; Olsen, Rolf Erik (Peer reviewed; Journal article, 2022)Moderate levels of intestinal damage and inflammation are often seen in intensive fish aquaculture. The causes may be due to antinutrients from plant meals, stress or other causes. There is currently a lack of good models ... -
Metabolic and molecular signatures of improved growth in Atlantic salmon (Salmo salar) fed surplus levels of methionine, folic acid, vitamin B6 and B12 throughout smoltification.
Adam, Anne-Catrin; Saito, Takaya; Espe, Marit; Whatmore, Paul; Fernandes, Jorge Manuel de Oliveira; Vikeså, Vibeke; Skjærven, Kaja Helvik (Peer reviewed; Journal article, 2021)A moderate surplus of the 1C nutrients methionine, folic acid, vitamin B6 and B12 above dietary recommendations for Atlantic salmon has shown to improve growth and reduce hepatosomatic index in the on-growing salt water ... -
Micronutrient supplementation affects DNA methylation in male gonads with potential intergenerational epigenetic inheritance involving the embryonic development through glutamate receptor-associated genes
Saito, Takaya; Whatmore, Paul; Taylor, John F.; Fernandes, Jorge Manuel de Oliveira; Adam, Anne-Catrin; Tocher, Douglas R.; Espe, Marit; Skjærven, Kaja Helvik (Peer reviewed; Journal article, 2022)DNA methylation has an important role in intergenerational inheritance. An increasing number of studies have reported evidence of germline inheritance of DNA methylation induced by nutritional signals in mammals. Vitamins ... -
Micronutrient supplementation affects transcriptional and epigenetic regulation of lipid metabolism in a dose-dependent manner
Saito, Takaya; Whatmore, Paul; Taylor, John F.; Fernandes, Jorge Manuel de Oliveira; Adam, Anne-Catrin; Tocher, Douglas R.; Espe, Marit; Skjærven, Kaja Helvik (Peer reviewed; Journal article, 2020) -
Mid and hindgut transcriptome profiling analysis of Atlantic salmon (Salmon salar) under unpredictable chronic stress
Løvmo, Signe Dille; Madaro, Angelico; Whatmore, Paul; Bardal, Tora; Østensen, Mari-Ann; Sandve, Simen Rød; Olsen, Rolf Erik (Peer reviewed; Journal article, 2020)The intestinal epithelium is a selectively permeable barrier for nutrients, electrolytes and water, while maintaining effective protection against pathogens. Combinations of stressors throughout an animal's life, especially ... -
Parental high dietary arachidonic acid levels modulated the hepatic transcriptome of adult zebrafish (Danio rerio) progeny
Adam, Anne-Catrin; Skjærven, Kaja Helvik; Whatmore, Paul; Moren, Mari; Lie, Kai Kristoffer (Journal article; Peer reviewed, 2018)Disproportionate high intake of n-6 polyunsaturated fatty acids (PUFAs) in the diet is considered as a major human health concern. The present study examines changes in the hepatic gene expression pattern of adult male ... -
Profiling DNA methylation patterns of zebrafish liver associated with parental high dietary arachidonic acid.
Adam, Anne-Catrin; Lie, Kai Kristoffer; Whatmore, Paul; Jakt, Lars Martin; Moren, Mari; Skjærven, Kaja Helvik (Journal article; Peer reviewed, 2019)Diet has been shown to influence epigenetic key players, such as DNA methylation, which can regulate the gene expression potential in both parents and offspring. Diets enriched in omega-6 and deficient in omega-3 PUFAs ... -
Red and white chinook salmon (Oncorhynchus tshawytscha): Differences in the transcriptome profile of muscle, liver, and pylorus
Madaro, Angelico; Torrissen, Ole; Whatmore, Paul; Lall, Santosh P.; Schmeisser, Jerome; Verlhac Trichet, Viviane; Olsen, Rolf Erik (Peer reviewed; Journal article, 2020)Astaxanthin (Ax), the main carotenoid responsible for the distinct red flesh color in salmonids (Oncorhynchus, Salvelinus, Salmo, and Parahucho), is added to the diet of farmed fish at a substantial cost. Despite the great ... -
Transcriptome profiling of lentil (Lens culinaris) through the first 24 hours of Ascochyta lentis infection reveals key defence response genes
Khorramdelazad, Mahsa; Bar, Ido; Whatmore, Paul; Smetham, Gabrielle; Bhaaskaria, Vijay; Yang, Yuedong; Bai, Shahla Hosseini; Mantri, Nitin; Zhou, Yaoqi; Ford, Rebecca (Journal article; Peer reviewed, 2018)Ascochyta blight, caused by the fungus Ascochyta lentis, is one of the most destructive lentil diseases worldwide, resulting in over $16 million AUD annual loss in Australia alone. The use of resistant cultivars is currently ...