Browsing Brage IMR by Author "Goksøyr, Anders"
Now showing items 1-20 of 22
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Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars)
Söderström, Sofie Karin; Lille-Langøy, Roger; Yadetie, Fekadu; Rauch, Mateusz; Milinski, Ana; Dejaegere, Annick; Stote, Roland H.; Goksøyr, Anders; Karlsen, Odd André (Peer reviewed; Journal article, 2022)Toxicity mediated by per- and polyfluoroalkyl substances (PFAS), and especially perfluoroalkyl acids (PFAAs), has been linked to activation of peroxisome proliferator-activated receptors (Ppar) in many vertebrates. Here, ... -
Attuning to a changing ocean
Stenseth, Nils Christian; Payne, Mark R.; Bonsdorff, Erik; Dankel, Dorothy Jane; Durant, Joel Marcel; Anderson, Leif G.; Armstrong, Claire W.; Blenckner, Thorsten; Brakstad, Ailin; Dupont, Sam; Eikeset, Anne Maria; Goksøyr, Anders; Jónsson, Steingrímur; Kuparinen, Anna; Våge, Kjetil; Österblom, Henrik; Paasche, Øyvind (Peer reviewed; Journal article, 2020)The ocean is a lifeline for human existence, but current practices risk severely undermining ocean sustainability. Present and future social−ecological challenges necessitate the maintenance and development of knowledge ... -
Benefit and risk assessment of fish in the Norwegian diet - Scientific Opinion of the Steering Committee of the Norwegian Scientific Committee for Food and Environment
Andersen, Lene Frost; Berstad, Paula; Bukhvalova, Barbara Alexandra; Carlsen, Monica Hauger; Dahl, Lisbeth Jane; Goksøyr, Anders; Sletting Jakobsen, Lea; Knutsen, Helle Katrine; Kvestad, Ingrid; Lillegaard, Inger Therese Laugsand; Mangschou, Bente; Meyer, Haakon Eduard; Parr, Christine Louise; Rakkestad, Kirsten Eline; Rasinger, Josef; Sengupta, Sayantan; Skeie, Guri; Starrfelt, Jostein; Ulven, Stine Marie (Peer reviewed; Journal article, 2022) -
Benefit and risk assessment of fish in the Norwegian diet - Scientific Opinion of the Steering Committee of the Norwegian Scientific Committee for Food and Environment
Andersen, Lene Frost; Berstad, Paula; Bukhvalova, Barbara Alexandra; Carlsen, Monica Hauger; Dahl, Lisbeth Jane; Goksøyr, Anders; Jakobsen, Lea Sletting; Knutsen, Helle Katrine; Kvestad, Ingrid; Lillegaard, Inger Therese Laugsand; Mangschou, Bente; Meyer, Haakon Eduard; Parr, Christine Louise; Rakkestad, Kirsten Eline; Rasinger, Josef; Sengupta, Sayantan; Skeie, Guri; Starrfelt, Jostein; Ulven, Stine Marie; Agdestein, Angelika; Bodin, Johanna Eva; Bruzell, Ellen Merete; Elvevoll, Edel O.; Hemre, Gro Ingunn; Hessen, Dag Olav; Husøy, Trine; Krogdahl, Åshild; Nilsen, Asbjørn Magne; Skjerdal, Olaug Taran; Steffensen, Inger-Lise; Strand, Tor Arne; Vandvik, Vigdis; Velle, Gaute; Wasteson, Yngvild; Alexander, Jan (Peer reviewed; Journal article, 2022) -
Co-Exposure of Phenanthrene and the cyp-Inducer 3-Methylchrysene Leads to Altered Biotransformation and Increased Toxicity in Fish Egg and Larvae
Donald, Carey; Sørhus, Elin; Perrichon, Prescilla; Nakken, Charlotte L.; Goksøyr, Anders; Jørgensen, Kåre Bredeli; Mayer, Philipp; da Silva, Denis A.M.; Meier, Sonnich (Peer reviewed; Journal article, 2023)Polycyclic aromatic hydrocarbons (PAHs) have frequently been suspected of governing crude oil toxicity because of similar morphological defects in fish. However, PAH concentrations are often not high enough to explain the ... -
Development of Atlantic cod (Gadus morhua) exposed to produced water during early life stages: Effects on embryos, larvae, and juvenile fish
Meier, Sonnich; Morton, H. Craig; Nyhammer, Gunnar; Grøsvik, Bjørn Einar; Makhotin, Valeri; Geffen, Audrey J.; Boitsov, Stepan; Kvestad, Karen Anita; Bohne-Kjersem, Anneli; Goksøyr, Anders; Folkvord, Arild; Klungsøyr, Jarle; Svardal, Asbjørn Martin (Journal article; Peer reviewed, 2010-08-21)Produced water (PW) contains numerous toxic compounds of natural origin, such as dispersed oil, metals, alkylphenols (APs), and polycyclic aromatic hydrocarbons (PAHs). In addition, PW also contains many different chemicals ... -
Effects of Agricultural Pesticides in Aquafeeds on Wild Fish Feeding on Leftover Pellets Near Fish Farms
Olsvik, Pål Asgeir; Larsen, Anett Kristin; Berntssen, Marc; Goksøyr, Anders; Karlsen, Odd Andre; Yadetie, Fekadu; Sanden, Monica; Kristensen, Torstein (Others, 2019)Screening has revealed that modern-day feeds used in Atlantic salmon aquaculture might contain trace amounts of agricultural pesticides. To reach slaughter size, salmon are produced in open net pens in the sea. Uneaten ... -
Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms
Olsvik, Pål Asgeir; Larsen, Anett Kristin; Berntssen, Marc; Goksøyr, Anders; Karlsen, Odd Andre; Yadetie, Fekadu; Sanden, Monica; Kristensen, Torstein (Journal article; Peer reviewed, 2019)Screening has revealed that modern-day feeds used in Atlantic salmon aquaculture might contain trace amounts of agricultural pesticides. To reach slaughter size, salmon are produced in open net pens in the sea. Uneaten ... -
Environmental effects of offshore produced water discharges: A review focused on the Norwegian continental shelf
Beyer, Jonny; Goksøyr, Anders; Hjermann, Dag Øystein; Klungsøyr, Jarle (Peer reviewed; Journal article, 2020)Produced water (PW), a large byproduct of offshore oil and gas extraction, is reinjected to formations or discharged to the sea after treatment. The discharges contain dispersed crude oil, polycyclic aromatic hydrocarbons ... -
Environmentally realistic concentrations of chlorinated, brominated, and fluorinated persistent organic pollutants induce the unfolded protein response as a shared stress pathway in the liver of Atlantic cod (Gadus morhua)
Olsvik, Pål Asgeir; Meier, Sonnich; Zhang, Xiaokang; Goksøyr, Anders; Karlsen, Odd André; Yadetie, Fekadu (Peer reviewed; Journal article, 2023)In the North Sea and North Atlantic coastal areas, fish experience relatively high background levels of persistent organic pollutants. This study aimed to compare the mode of action of environmentally relevant concentrations ... -
Expression and localization of the aryl hydrocarbon receptors and cytochrome P450 1A during early development of Atlantic cod (Gadus morhua)
Aranguren Abadía, Libe; Donald, Carey; Eilertsen, Mariann; Gharbi, Naouel; Tronci, Valentina; Sørhus, Elin; Mayer, Philipp; Nilsen, Tom Ole; Meier, Sonnich; Goksøyr, Anders; Karlsen, Odd Andre (Peer reviewed; Journal article, 2020)The aryl hydrocarbon receptor (Ahr) is a ligand-activated transcription factor that mediates the toxicity of dioxins and dioxin-like compounds (DLCs) in vertebrates. Two clades of the Ahr family exist in teleosts (Ahr1 and ... -
Integrative omics-analysis of lipid metabolism regulation by peroxisome proliferator-activated receptor a and b agonists in male Atlantic cod
Eide, Marta; Goksøyr, Anders; Yadetie, Fekadu; Gilabert, Alejandra; Bartosova, Zdenka; Frøysa, Håvard Guldbrandsen; Fallahi, Shirin; Zhang, Xiaokang; Blaser, Nello; Jonassen, Inge; Bruheim, Per; Alendal, Guttorm; Brun, Morten; Porte, Cinta; Karlsen, Odd André (Peer reviewed; Journal article, 2023)Lipid metabolism is essential in maintaining energy homeostasis in multicellular organisms. In vertebrates, the peroxisome proliferator-activated receptors (PPARs, NR1C) regulate the expression of many genes involved in ... -
Intestinal permeability and gene expression after polyethylene and polyamide microplastic ingestion in Wistar rats.
Toto, Benuarda; Refosco, Alice; O'Keeffe, Maria; Barkhald, Øyvind Halås; Brønstad, Aurora Margrethe; Lied, Gülen Arslan; Yadetie, Fekadu; Goksøyr, Anders; Kögel, Tanja; Dierkes, Jutta (Peer reviewed; Journal article, 2022) -
Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua)
Aranguren Abadía, Libe; Yadetie, Fekadu; Donald, Carey; Sørhus, Elin; Myklatun, Lars Eirik; Zhang, Xiaokang; Lie, Kai Kristoffer; Perrichon, Prescilla; Nakken, Charlotte Langeland; Durif, Caroline; Shema, Steven; Browman, Howard; Skiftesvik, Anne Berit; Goksøyr, Anders; Meier, Sonnich; Karlsen, Odd André (Peer reviewed; Journal article, 2022)Photo-enhanced toxicity of crude oil is produced by exposure to ultraviolet (UV) radiation. Atlantic cod (Gadus morhua) embryos were exposed to crude oil with and without UV radiation (290–400 nm) from 3 days post fertilization ... -
Polycyclic aromatic hydrocarbons modulate the activity of Atlantic cod (Gadus morhua) vitamin D receptor paralogs in vitro
Goksøyr, Siri Øfsthus; Goldstone, Jed; Lille-Langøy, Roger; Lock, Erik Jan Robert; Olsvik, Pål Asgeir; Goksøyr, Anders; Karlsen, Odd André (Peer reviewed; Journal article, 2021)Vitamin D receptor (VDR) mediates the biological function of the steroid hormone calcitriol, which is the metabolically active version of vitamin D. Calcitriol is important for a wide array of physiological functions, ... -
Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua)
Dale, Karina; Yadetie, Fekadu; Müller, Mette Helen Bjørge; Pampanin, Daniela Maria; Gilabert, Alejandra; Zhang, Xiaokang; Tairova, Zhanna; Haarr, Ane; Lille-Langøy, Roger; Lyche, Jan Ludvig; Porte, Cinta; Karlsen, Odd Andre; Goksøyr, Anders (Peer reviewed; Journal article, 2020)The aim of the present study was to investigate effects of defined mixtures of polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs), at low, environmentally relevant (1× = L), or high (20× = H) ... -
Protocol and description of literature searches for the risk-benefit assessment of fish in the Norwegian diet. The Steering Committee of the Norwegian Scientific Committee for Food and Environment
Andersen, Lene Frost; Berstad, Paula; Carlsen, Monica Hauger; Dahl, Lisbeth; Goksøyr, Anders; Knutsen, Helle Katrine; Kvestad, Ingrid; Lillegaard, Inger Therese Laugsand; Mangschou, Bente; Meyer, Haakon E; Nauta, Maarten; Rakkestad, Kirsten Eline; Rasinger, Josef Daniel; Skeie, Guri; Starrfelt, Jostein; Thomsen, Sofie; Ulven, Stine Marie; Agdestein, Angelika; Bodin, Johanna Eva; Elvevoll, Edel O.; Hessen, Dag Olav; Husøy, Trine; Krogdahl, Åshild; Nilsen, Asbjørn Magne; Skjerdal, Olaug Taran; Steffensen, Inger-Lise Karin; Strand, Tor A; Velle, Gaute; Wasteson, Yngvild; Hemre, Gro Ingunn; Vandvik, Vigdis; Alexander, Jan (Research report, 2020) -
ReCodLiver0.9: Overcoming Challenges in Genome-Scale Metabolic Reconstruction of a Non-model Species
Hanna, Eileen Marie; Zhang, Xiaokang; Eide, Marta; Fallahi, Shirin; Furmanek, Tomasz; Yadetie, Fekadu; Zielinski, Daniel Craig; Goksøyr, Anders; Jonassen, Inge (Peer reviewed; Journal article, 2020)The availability of genome sequences, annotations, and knowledge of the biochemistry underlying metabolic transformations has led to the generation of metabolic network reconstructions for a wide range of organisms in ... -
Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua)
Dale, Karina; Yadetie, Fekadu; Horvli, Torill; Zhang, Xiaokang; Frøysa, Håvard G; Karlsen, Odd André; Goksøyr, Anders (Peer reviewed; Journal article, 2022)The aim of the present study was to investigate effects of per- and polyfluoroalkyl substances (PFAS), both single compounds and a mixture of these, using precision-cut liver slices (PCLS) from Atlantic cod (Gadus morhua). ... -
Spawning time in adult polar cod (Boreogadus saida) altered by crude oil exposure, independent of food availability
Strople, Leah Catherine; Vieweg, Ireen; Yadetie, Fekadu; Odei, Derrick Kwame; Thorsen, Anders; Karlsen, Odd André; Goksøyr, Anders; Sørensen, Lisbet; Sarno, Antonio; Hansen, Bjørn Henrik; Frantzen, marianne; Hansen, Øyvind J; Puvanendran, Velmurugu; Nahrgang, Jasmine (Peer reviewed; Journal article, 2023)Fish early life stages are well known for their sensitivity to crude oil exposure. However, the effect of crude oil exposure on adults and their gametes during their spawning period is not well studied. Polar cod, a key ...