Blar i Brage IMR på forfatter "Ebmeyer, Johanna"
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Hepatotoxic pyrrolizidine alkaloids induce DNA damage response in rat liver in a 28-day feeding study
Ebmeyer, Johanna; Rasinger, Josef; Hengstler, Jan G.; Schaudien, Dirk; Creutzenberg, Otto; Lampen, Alfonso; Braeuning, Albert; Hassel-Pras, Stefanie (Peer reviewed; Journal article, 2020)Pyrrolizidine alkaloids (PA) are secondary plant metabolites that occur as food and feed contaminants. Acute and subacute PA poisoning can lead to severe liver damage in humans and animals, comprising liver pain, hepatomegaly ... -
Pyrrolizidine alkaloid-induced transcriptomic changes in rat lungs in a 28-day subacute feeding study
Buchmueller, Julia; Sprenger, Heike; Ebmeyer, Johanna; Rasinger, Josef; Creutzenberg, Otto; Schaudien, Dirk; Hengstler, Jan G.; Guenther, Georgia; Braeuning, Albert; Hessel-Pras, Stefanie (Peer reviewed; Journal article, 2021)Pyrrolizidine alkaloids (PAs) are secondary plant metabolites synthesized by a wide range of plants as protection against herbivores. These toxins are found worldwide and pose a threat to human health. PAs induce acute ...