Blar i Brage IMR på forfatter "Sørhus, Elin"
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Alkyl-phenanthrenes in early life stage fish: differential toxicity in Atlantic haddock (Melanogrammus aeglefinus) embryos
Donald, Carey; Nakken, Charlotte L.; Sørhus, Elin; Perrichon, Prescilla; Jørgensen, Kåre Bredeli; Bjelland, Hege K.; Stølen, Christine; Kancherla, Sindhu; Mayer, Philipp; Meier, Sonnich (Peer reviewed; Journal article, 2023)Tricyclic polycyclic aromatic hydrocarbons (PAHs) are believed to be the primary toxic components of crude oil. Such compounds including phenanthrene are known to have direct effects on cardiac tissue, which lead to ... -
Alkyl-phenanthrenes in early life stage fish: differential toxicity in Atlantic haddock (Melanogrammus aeglefinus) embryos
Donald, Carey; Nakken, Charlotte L.; Sørhus, Elin; Perrichon, Prescilla; Jørgensen, Kåre Bredeli; Bjelland, Hege Kristoffersen; Stølen, Christine; Kancherla, Sindhu; Mayer, Philipp; Meier, Sonnich (Peer reviewed; Journal article, 2023)Tricyclic polycyclic aromatic hydrocarbons (PAHs) are believed to be the primary toxic components of crude oil. Such compounds including phenanthrene are known to have direct effects on cardiac tissue, which lead to ... -
Cardiac dysfunction affects eye development and vision by reducing supply of lipids in fish
Sørhus, Elin; Meier, Sonnich; Donald, Carey; Furmanek, Tomasz; Edvardsen, Rolf Brudvik; Lie, Kai Kristoffer (Peer reviewed; Journal article, 2021)Developing organisms are especially vulnerable to environmental stressors. Crude oil exposure in early life stages of fish result in multiple functional and developmental defects, including cardiac dysfunction and abnormal ... -
Co-exposure to UV radiation and crude oil increases acute embryotoxicity and sublethal malformations in the early life stages of Atlantic haddock (Melanogrammus aeglefinus)
Sørhus, Elin; Donald, Carey; Nakken, Charlotte L.; Perrichon, Prescilla; Durif, Caroline; Shema, Steven; Browman, Howard; Skiftesvik, Anne Berit; Lie, Kai Kristoffer; Rasinger, Josef; Müller, Mette Helen Bjørge; Meier, Sonnich (Peer reviewed; Journal article, 2023)Crude oil causes severe abnormalities in developing fish. Photomodification of constituents in crude oil increases its toxicity several fold. We report on the effect of crude oil, in combination with ultraviolet (UV) ... -
Crude oil exposures reveal roles for intracellular calcium cycling in haddock craniofacial and cardiac development
Sørhus, Elin; Incardona, John P.; Karlsen, Ørjan; Linbo, Tiffany; Sørensen, Lisbet; Nordtug, Trond; van der Meeren, Terje; Thorsen, Anders; Thorbjørnsen, Maja; Jentoft, Sissel; Edvardsen, Rolf; Meier, Sonnich (Journal article; Peer reviewed, 2016-08-10)Recent studies have shown that crude oil exposure affects cardiac development in fish by disrupting excitation-contraction (EC) coupling. We previously found that eggs of Atlantic haddock (Melanogrammus aeglefinus) bind ... -
Differential developmental toxicity of crude oil in early life stages of Atlantic halibut (Hippoglossus hippoglossus)
Perrichon, Prescilla; Donald, Carey; Sørhus, Elin; Harboe, Torstein; Meier, Sonnich (Peer reviewed; Journal article, 2021)To further understand the complexity of developmental toxicity of dispersed oil and importance of exposure timing on fish early life stages, Atlantic halibut (Hippoglossus hippoglossus) were exposed to environmentally ... -
DNA damage and health effects in juvenile haddock (Melanogrammus aeglefinus) exposed to PAHs associated with oil-polluted sediment or produced water
Meier, Sonnich; Karlsen, Ørjan; Le Goff, Jérémie; Sørensen, Lisbet; Sørhus, Elin; Pampanin, Daniela Maria; Donald, Carey E.; Fjelldal, Per Gunnar; Dunaevskaya, Evgenia; Romano, Marta; Caliani, Ilaria; Casini, Silvia; Bogevik, Andre S.; Olsvik, Pål Asgeir; Myers, Mark; Grøsvik, Bjørn Einar (Peer reviewed; Journal article, 2020)The research objective was to study the presence of DNA damages in haddock exposed to petrogenic or pyrogenic polyaromatic hydrocarbons (PAHs) from different sources: 1) extracts of oil produced water (PW), dominated by ... -
Early ontogeny of the lesser sandeel (Ammodytes marinus)
Perrichon, Prescilla; Bjelland, Reidun Marie; Durif, Caroline; Fiksdal, Ingrid Uglenes; Johnsen, Espen; Skiftesvik, Anne Berit; Cresci, Alessandro; Browman, Howard; Sørhus, Elin (Peer reviewed; Journal article, 2023)Background Lesser sandeel (Ammodytes marinus) is widely distributed in North Sea ecosystems. Sandeel acts as a critical trophic link between zooplankton and top predators (fish, mammals, sea birds). Because they live buried ... -
Expression and localization of the aryl hydrocarbon receptors and cytochrome P450 1A during early development of Atlantic cod (Gadus morhua)
Aranguren Abadía, Libe; Donald, Carey; Eilertsen, Mariann; Gharbi, Naouel; Tronci, Valentina; Sørhus, Elin; Mayer, Philipp; Nilsen, Tom Ole; Meier, Sonnich; Goksøyr, Anders; Karlsen, Odd Andre (Peer reviewed; Journal article, 2020)The aryl hydrocarbon receptor (Ahr) is a ligand-activated transcription factor that mediates the toxicity of dioxins and dioxin-like compounds (DLCs) in vertebrates. Two clades of the Ahr family exist in teleosts (Ahr1 and ... -
Genomic architecture of haddock (Melanogrammus aeglefinus) shows expansions of innate immune genes and short tandem repeats
Tørresen, Ole K.; Brieuc, Marine Servane; Solbakken, Monica Hongrø; Sørhus, Elin; Nederbragt, Alexander Johan; Jakobsen, Kjetill Sigurd; Meier, Sonnich; Edvardsen, Rolf; Jentoft, Sissel (Journal article; Peer reviewed, 2018)Increased availability of genome assemblies for non-model organisms has resulted in invaluable biological and genomic insight into numerous vertebrates, including teleosts. Sequencing of the Atlantic cod (Gadus morhua) ... -
Kunnskapsstatus for havsil i norsk sone av Nordsjøen
Johnsen, Espen; Sørhus, Elin; de Jong, Karen; Lie, Kai Kristoffer; Grøsvik, Bjørn Einar (Rapport fra havforskningen;2021 - 33, Research report, 2021)Tobis eller havsil er en nøkkelart i økosystemet i Nordsjøen, og viktige gyte- og leveområder for havsil er identifisert som særlig verdifulle og sårbare områder (SVO) i Nordsjøen. Rapporten oppsummerer eksisterende kunnskap ... -
Magnetic fields generated by the DC cables of offshore wind farms have no effect on spatial distribution or swimming behavior of lesser sandeel larvae (Ammodytes marinus)
Cresci, Alessandro; Perrichon, Prescilla; Durif, Caroline; Sørhus, Elin; Johnsen, Espen; Bjelland, Reidun Marie; Larsen, Torkel; Skiftesvik, Anne Berit; Browman, Howard (Peer reviewed; Journal article, 2022)In the North Sea, the number and size of offshore wind (OW) turbines, together with the associated network of High Voltage Direct Current (HVDC) subsea cables, will increase rapidly over the coming years. HVDC cables produce ... -
Mind the gap – Relevant design for laboratory oil exposure of fish as informed by a numerical impact assessment model
Frøysa, Håvard Guldbrandsen; Nepstad, Raymond; Meier, Sonnich; Donald, Carey; Sørhus, Elin; Bockwoldt, Mathias; Carroll, JoLynn; Vikebø, Frode Bendiksen (Peer reviewed; Journal article, 2023)Laboratory experiments provide knowledge of species-specific effects thresholds that are used to parameterize impact assessment models of oil contamination on marine ecosystems. Such experiments typically place individuals ... -
Novel adverse outcome pathways revealed by chemical genetics in a developing marine fish
Sørhus, Elin; Incardona, John P.; Furmanek, Tomasz; Goetz, Giles W.; Scholz, Nathaniel; Meier, Sonnich; Edvardsen, Rolf; Jentoft, Sissel (Peer reviewed; Journal article, 2017)Crude oil spills are a worldwide ocean conservation threat. Fish are particularly vulnerable to the oiling of spawning habitats, and crude oil causes severe abnormalities in embryos and larvae. However, the underlying ... -
Offshore crude oil disrupts retinoid signaling and eye development in larval Atlantic haddock
Lie, Kai Kristoffer; Meier, Sonnich; Sørhus, Elin; Edvardsen, Rolf; Karlsen, Ørjan; Olsvik, Pål Asgeir (Journal article; Peer reviewed, 2019)The aim of this study was to examine the impact of dispersed crude oil on retinoid metabolism and signaling in developing haddock larvae (Melanogrammus aeglefinus). Retinoids and its active metabolites are involved in the ... -
Oil droplet fouling and differential toxicokinetics of polycyclic aromatic hydrocarbons in embryos of Atlantic haddock and cod
Sørensen, Lisbet; Sørhus, Elin; Nordtug, Trond; Incardona, John P.; Linbo, Tiffany; Giovanetti, Laura; Karlsen, Ørjan; Meier, Sonnich (Peer reviewed; Journal article, 2017)The impact of crude oil pollution on early life stages (ELS) of fish, including larvae and embryos, has received considerable attention in recent years. Of the organic components present in crude oil, polycyclic aromatic ... -
Ontogeny-Specific Skeletal Deformities in Atlantic Haddock Caused by Larval Oil Exposure
Olsvik, Pål Asgeir; Sørhus, Elin; Meier, Sonnich; Torvanger, Ingrid; Thorbjørnsen, Maja; Thorsen, Anders; Sørensen, Lisbet; Fjelldal, Per Gunnar; Karlsen, Ørjan; Guimaraes, Igo G.; Lie, Kai Kristoffer (Peer reviewed; Journal article, 2021)Bone deformities are one of the main effects of crude oil exposure in marine fish larvae. Craniofacial and jaw deformities, if severe enough, may restrict feeding and ultimately kill the developing larvae. This study aimed ... -
Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua)
Aranguren Abadía, Libe; Yadetie, Fekadu; Donald, Carey; Sørhus, Elin; Myklatun, Lars Eirik; Zhang, Xiaokang; Lie, Kai Kristoffer; Perrichon, Prescilla; Nakken, Charlotte Langeland; Durif, Caroline; Shema, Steven; Browman, Howard; Skiftesvik, Anne Berit; Goksøyr, Anders; Meier, Sonnich; Karlsen, Odd André (Peer reviewed; Journal article, 2022)Photo-enhanced toxicity of crude oil is produced by exposure to ultraviolet (UV) radiation. Atlantic cod (Gadus morhua) embryos were exposed to crude oil with and without UV radiation (290–400 nm) from 3 days post fertilization ... -
Polyaromatic hydrocarbons in pollution: a heart-breaking matter
Marris, Charlotte; Kompella, Shiva N.; Miller, Mark M.; Incardona, John P.; Brette, Fabien; Hancox, Jules C.; Sørhus, Elin; Shiels, Holly A. (Journal article; Peer reviewed, 2019)Air pollution is associated with detrimental effects on human health, including decreased cardiovascular function. However, the causative mechanisms behind these effects have yet to be fully elucidated. Here we review the ... -
Sex differentiation in Atlantic cod (Gadus morhua L.): morphological and gene expression studies
Haugen, Trine; Almeida, Fernanda F. L.; Andersson, Eva; Bogerd, Jan; Male, Rune; Skaar, Katrine S.; Schulz, Rüdiger W.; Sørhus, Elin; Wijgerde, Tim; Taranger, Geir Lasse (Journal article; Peer reviewed, 2012-06-18)Background In differentiated gonochoristic species, a bipotential gonad develops into an ovary or testis during sex differentiation. Knowledge about this process is necessary to improve methods for masculinizing genetically ...