Browsing Brage IMR by Author "Incardona, John P."
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Biological Responses of Pacific Herring Embryos to Crude Oil Are Quantifiable at Exposure Levels Below Conventional Limits of Quantitation for PAHs in Water and Tissues
Incardona, John P.; Linbo, Tiffany L.; Cameron, James R.; French, Barbara L.; Bolton, Jennie L.; Gregg, Jacob L.; Donald, Carey; Hershberger, Paul K.; Scholz, Nathaniel L. (Peer reviewed; Journal article, 2023)Pacific herring (Clupea pallasii), a cornerstone of marine food webs, generally spawn on marine macroalgae in shallow nearshore areas that are disproportionately at risk from oil spills. Herring embryos are also highly ... -
Crude oil exposure of early life stages of Atlantic haddock suggests threshold levels for developmental toxicity as low as 0.1 μg total polyaromatic hydrocarbon (TPAH)/L
Sørhus, Elin; Sørensen, Lisbet; Grøsvik, Bjørn Einar; Le Goff, Jérémie; Incardona, John P.; Linbo, Tiffany; Baldwin, David; Karlsen, Ørjan; Nordtug, Trond; Hansen, Bjørn Henrik; Thorsen, Anders; Donald, Carey; van der Meeren, Terje; Robson, William; Rowland, Steven J.; Rasinger, Josef; Vikebø, Frode Bendiksen; Meier, Sonnich (Peer reviewed; Journal article, 2023)Atlantic haddock (Melanogrammus aeglefinus) embryos bind dispersed crude oil droplets to the eggshell and are consequently highly susceptible to toxicity from spilled oil. We established thresholds for developmental toxicity ... -
Crude oil exposures reveal roles for intracellular calcium cycling in haddock craniofacial and cardiac development
Sørhus, Elin; Incardona, John P.; Karlsen, Ørjan; Linbo, Tiffany; Sørensen, Lisbet; Nordtug, Trond; van der Meeren, Terje; Thorsen, Anders; Thorbjørnsen, Maja; Jentoft, Sissel; Edvardsen, Rolf; Meier, Sonnich (Journal article; Peer reviewed, 2016-08-10)Recent studies have shown that crude oil exposure affects cardiac development in fish by disrupting excitation-contraction (EC) coupling. We previously found that eggs of Atlantic haddock (Melanogrammus aeglefinus) bind ... -
Embryonic crude oil exposure impairs growth and lipid allocation in a keystone Arctic forage fish
Laurel, Benjamin J.; Copeman, Louise; Iseri, Paul; Spencer, Mari; Hutchinson, Greg; Nordtug, Trond; Donald, Carey; Meier, Sonnich; Allan, Sarah; Boyd, Daryle; Ylitalo, Gina; Cameron, James; French, Babara; Linbo, Tiffany; Scholz, Nathaniel; Incardona, John P. (Journal article; Peer reviewed, 2019)As Arctic ice recedes, future oil spills pose increasing risk to keystone species and the ecosystems they support. We show that Polar cod (Boreogadus saida), an energy-rich forage fish for marine mammals, seabirds, and ... -
Novel adverse outcome pathways revealed by chemical genetics in a developing marine fish
Sørhus, Elin; Incardona, John P.; Furmanek, Tomasz; Goetz, Giles W.; Scholz, Nathaniel; Meier, Sonnich; Edvardsen, Rolf; Jentoft, Sissel (Peer reviewed; Journal article, 2017)Crude oil spills are a worldwide ocean conservation threat. Fish are particularly vulnerable to the oiling of spawning habitats, and crude oil causes severe abnormalities in embryos and larvae. However, the underlying ... -
Oil droplet fouling and differential toxicokinetics of polycyclic aromatic hydrocarbons in embryos of Atlantic haddock and cod
Sørensen, Lisbet; Sørhus, Elin; Nordtug, Trond; Incardona, John P.; Linbo, Tiffany; Giovanetti, Laura; Karlsen, Ørjan; Meier, Sonnich (Peer reviewed; Journal article, 2017)The impact of crude oil pollution on early life stages (ELS) of fish, including larvae and embryos, has received considerable attention in recent years. Of the organic components present in crude oil, polycyclic aromatic ... -
Polyaromatic hydrocarbons in pollution: a heart-breaking matter
Marris, Charlotte; Kompella, Shiva N.; Miller, Mark M.; Incardona, John P.; Brette, Fabien; Hancox, Jules C.; Sørhus, Elin; Shiels, Holly A. (Journal article; Peer reviewed, 2019)Air pollution is associated with detrimental effects on human health, including decreased cardiovascular function. However, the causative mechanisms behind these effects have yet to be fully elucidated. Here we review the ...