• Atlantic salmon populations reveal adaptive divergence of immune related genes - A duplicated genome under selection 

      Kjærner-Semb, Erik Nordtorp; Ayllon, Fernando; Furmanek, Tomasz; Wennevik, Vidar; Dahle, Geir; Niemelä, Eero; Ozerov, Mikhail; Vähä, Juha-Pekka; Glover, Kevin; Rubin, Carl J.; Wargelius, Anna; Edvardsen, Rolf (Journal article, 2016)
    • Cardiac dysfunction affects eye development and vision by reducing supply of lipids in fish 

      Sørhus, Elin; Meier, Sonnich; Donald, Carey; Furmanek, Tomasz; Edvardsen, Rolf Brudvik; Lie, Kai Kristoffer (Peer reviewed; Journal article, 2021)
      Developing organisms are especially vulnerable to environmental stressors. Crude oil exposure in early life stages of fish result in multiple functional and developmental defects, including cardiac dysfunction and abnormal ...
    • Comparative transcriptome analysis of trout skin pigment cells 

      Djurdjevic, Ida; Furmanek, Tomasz; Miyazawa, Seita; Susnik Bajec, Simona (Journal article; Peer reviewed, 2019)
      Background Enormous variability in skin colour and patterning is a characteristic of teleost fish, including Salmonidae fishes, which present themselves as a suitable model for studying mechanisms of pigment patterning. ...
    • Comparison of anadromous and landlocked Atlantic salmon genomes reveals signatures of parallel and relaxed selection across the Northern Hemisphere 

      Kjærner-Semb, Erik Nordtorp; Edvardsen, Rolf Brudvik; Ayllon, Fernando; Vogelsang, Petra; Furmanek, Tomasz; Rubin, Carl-Johan; Veselov, Alexey E.; Nilsen, Tom Ole; McCormick, Stephen D.; Primmer, Craig R.; Wargelius, Anna (Peer reviewed; Journal article, 2020)
      Most Atlantic salmon (Salmo salar L.) populations follow an anadromous life cycle, spending early life in freshwater, migrating to the sea for feeding, and returning to rivers to spawn. At the end of the last ice age ~10,000 ...
    • Diet affects the redox system in developing Atlantic cod(Gadus morhua) larvae 

      Penglase, Samuel; Edvardsen, Rolf; Furmanek, Tomasz; Rønnestad, Ivar; Karlsen, Ørjan; van der Meeren, Terje; Hamre, Kristin (Journal article; Peer reviewed, 2015-06-12)
      The growth and development of marine fish larvae fed copepods is superior to those fed rotifers, but the underlying molecular reasons for this are unclear. In the following study we compared the effects of such diets on ...
    • Full production cycle performance of gene-edited, sterile Atlantic salmon - growth, smoltification, welfare indicators and fillet composition 

      Kleppe, Lene; Fjelldal, Per Gunnar; Andersson, Eva; Hansen, Tom Johnny; Sanden, Monica; Bruvik, Aina; Skaftnesmo, Kai Ove; Furmanek, Tomasz; Kjærner-Semb, Erik Nordtorp; Crespo, Diego; Flavell, Simon; Pedersen, Audun Østby; Vogelsang, Petra; Torsvik, Anja; Kvestad, Karen Anita; Olausson, Sara; Norberg, Birgitta; Schulz, Rüdiger W.; Bogerd, J.; Santi, N.; Edvardsen, Rolf Brudvik; Wargelius, Anna (Peer reviewed; Journal article, 2022)
      Using germ cell-free (GCF), sterile, dnd-knockout salmon for farming could solve the problems associated with precocious maturation and genetic introgression of farmed breeds into wild populations. However, prior to using ...
    • Genome sequencing Part 1. Final report, April 2013 

      Skern-Mauritzen, Rasmus; Malde, Ketil; Furmanek, Tomasz; Nilsen, Frank (Rapport fra Havforskningen;Nr. 11-2013, Working paper, 2013)
    • Heterochiasmy and the establishment of gsdf as a novel sex determining gene in Atlantic halibut 

      Edvardsen, Rolf Brudvik; Wallerman, Ola; Furmanek, Tomasz; Kleppe, Lene; Jern, Patric; Wallberg, Andreas; Kjærner-Semb, Erik Nordtorp; Mæhle, Stig; Olausson, Sara; Sundström, Elisabeth; Harboe, Torstein; Mangor-Jensen, Ragnfrid; Drønen, Margareth Møgster; Perrichon, Prescilla; Norberg, Birgitta; Rubin, Carl-Johan (Peer reviewed; Journal article, 2022)
      Atlantic Halibut (Hippoglossus hippoglossus) has a X/Y genetic sex determination system, but the sex determining factor is not known. We produced a high-quality genome assembly from a male and identified parts of chromosome ...
    • Illuminating the planktonic stages of salmon lice: A unique fluorescence signal for rapid identification of a rare copepod in zooplankton assemblages 

      Thompson, Cameron; Bron, James E.; Bui, Samantha; Dalvin, Sussie; Fordyce, Mark; Furmanek, Tomasz; Nordi, Gunnvør á; Skern-Mauritzen, Rasmus (Peer reviewed; Journal article, 2021)
      Monitoring of planktonic salmon louse (Lepeophtheirus salmonis salmonis) abundance and parameterization of key life-history traits has been hindered by labour-intensive and error-prone quantification using traditional light ...
    • Increasing Sequence Search Sensitivity with Transitive Alignments 

      Malde, Ketil; Furmanek, Tomasz (Journal article; Peer reviewed, 2013-02-14)
      Sequence alignment is an important bioinformatics tool for identifying homology, but searching against the full set of available sequences is likely to result in many hits to poorly annotated sequences providing very little ...
    • Insulin-like 3 affects zebrafish spermatogenic cells directly and via Sertoli cells 

      Crespo, Diego; Assis, Luiz H. C.; Zhang, Yu Ting; Safian, Diego; Furmanek, Tomasz; Skaftnesmo, Kai Ove; Norberg, Birgitta; Ge, Wei; Choi, Yung-Ching; den Broeder, Marjo J.; Legler, Juliette; Bogerd, Jan; Schulz, Rüdiger W (Peer reviewed; Journal article, 2021)
      Pituitary hormones can use local signaling molecules to regulate target tissue functions. In adult zebrafish testes, follicle-stimulating hormone (Fsh) strongly increases the production of insulin-like 3 (Insl3), a Leydig ...
    • Integrative testis transcriptome analysis reveals differentially expressed miRNAs and their mRNA targets during early puberty in Atlantic salmon 

      Skaftnesmo, Kai Ove; Edvardsen, Rolf; Furmanek, Tomasz; Crespo, D.; Andersson, Eva; Kleppe, Lene; Taranger, Geir Lasse; Bogerd, Jan; Schulz, Rüdiger W.; Wargelius, Anna (Peer reviewed; Journal article, 2017)
    • Maternal 3’UTRs: from egg to onset of zygotic transcription in Atlantic cod 

      Kleppe, Lene; Edvardsen, Rolf B.; Kuhl, Heiner; Malde, Ketil; Furmanek, Tomasz; Drivenes, Øyvind; Reinhardt, Richard; Taranger, Geir Lasse; Wargelius, Anna (Journal article; Peer reviewed, 2012-09-01)
      Background Zygotic transcription in fish embryos initiates around the time of gastrulation, and all prior development is initiated and controlled by maternally derived messenger RNAs. Atlantic cod egg and embryo viability ...
    • Novel adverse outcome pathways revealed by chemical genetics in a developing marine fish 

      Sørhus, Elin; Incardona, John P.; Furmanek, Tomasz; Goetz, Giles W.; Scholz, Nathaniel; Meier, Sonnich; Edvardsen, Rolf; Jentoft, Sissel (Peer reviewed; Journal article, 2017)
      Crude oil spills are a worldwide ocean conservation threat. Fish are particularly vulnerable to the oiling of spawning habitats, and crude oil causes severe abnormalities in embryos and larvae. However, the underlying ...
    • Photoreception and transcriptomic response to light during early development of a teleost with a life cycle tightly controlled by seasonal changes in photoperiod 

      Eilertsen, Mariann; Dolan, David William Peter; Bolton, Charlotte M.; Karlsen, Rita; Davies, Wayne I.L.; Edvardsen, Rolf Brudvik; Furmanek, Tomasz; Sveier, Harald; Migaud, Herve; Helvik, Jon Vidar (Peer reviewed; Journal article, 2022)
      Light cues vary along the axis of periodicity, intensity and spectrum and perception of light is dependent on the photoreceptive capacity encoded within the genome and the opsins expressed. A global approach was taken to ...
    • Quantitative proteome profiling reveals molecular hallmarks of egg quality in Atlantic halibut: impairments of transcription and protein folding impede protein and energy homeostasis during early development 

      Yilmaz, Ozlem; Mangor-Jensen, Anders; Harboe, Torstein; Drønen, Margareth Møgster; Mangor-Jensen, Ragnfrid; Mjaavatten, Olav; Birkeland, Even; Spriet, Endy; Sandven, Linda; Furmanek, Tomasz; Berven, Frode Steingrimsen; Wargelius, Anna; Norberg, Birgitta (Peer reviewed; Journal article, 2022)
      Tandem mass tag spectrometry (TMT labeling-LC-MS/MS) was utilized to examine the global proteomes of Atlantic halibut eggs at the 1-cell-stage post fertilization. Comparisons were made between eggs judged to be of good ...
    • ReCodLiver0.9: Overcoming Challenges in Genome-Scale Metabolic Reconstruction of a Non-model Species 

      Hanna, Eileen Marie; Zhang, Xiaokang; Eide, Marta; Fallahi, Shirin; Furmanek, Tomasz; Yadetie, Fekadu; Zielinski, Daniel Craig; Goksøyr, Anders; Jonassen, Inge (Peer reviewed; Journal article, 2020)
      The availability of genome sequences, annotations, and knowledge of the biochemistry underlying metabolic transformations has led to the generation of metabolic network reconstructions for a wide range of organisms in ...
    • RNA deep sequencing of the Atlantic cod transcriptome 

      Johansen, Steinar D.; Karlsen, Bård Ove; Furmanek, Tomasz; Andreassen, Morten; Jørgensen, Tor Erik; Bizuayehu, Teshome T.; Breines, Ragna; Emblem, Åse; Kettunen, Päivi; Luukko, Keijo; Edvardsen, Rolf B.; Nordeide, Jarle Tryti; Coucheron, Dag H.; Moum, Truls (Journal article; Peer reviewed, 2010-05-20)
      The Atlantic cod (Gadus morhua) is an emerging aquaculture species. Efforts to develop and characterize its genomic recourses, including draft-grade genome sequencing, have been initiated by the research community. The ...
    • RNA deep sequencing of the Atlantic cod transcriptome 

      Johansen, Steinar D.; Karlsen, Bård Ove; Furmanek, Tomasz; Andreassen, Morten; Jørgensen, Tor Erik; Bizuayehu, Teshome T.; Breines, Ragna; Emblem, Åse; Kettunen, Päivi; Luukko, Keijo; Edvardsen, Rolf B.; Nordeide, Jarle Tryti; Coucheron, Dag H.; Moum, Truls (Journal article; Peer reviewed, 2010-05-20)
      The Atlantic cod (Gadus morhua) is an emerging aquaculture species. Efforts to develop and characterize its genomic recourses, including draft-grade genome sequencing, have been initiated by the research community. The ...
    • The salmon louse genome: Copepod features and parasitic adaptations 

      Skern-Mauritzen, Rasmus; Malde, Ketil; Eichner, Christiane; Dondrup, Michael; Furmanek, Tomasz; Besnier, Francois; Komisarczuk, Anna Zofia; Nuhn, Michael; Dalvin, Sussie; Edvardsen, Rolf Brudvik; Klages, Sven; Huettel, Bruno; Stueber, Kurt; Grotmol, Sindre; Karlsbakk, Egil Erlingsson; Kersey, Paul; Leong, Jong S; Glover, Kevin Alan; Reinhardt, Richard; Lien, Sigbjørn; Jonassen, Inge; Koop, Ben F; Nilsen, Frank (Peer reviewed; Journal article, 2021)
      Copepods encompass numerous ecological roles including parasites, detrivores and phytoplankton grazers. Nonetheless, copepod genome assemblies remain scarce. Lepeophtheirus salmonis is an economically and ecologically ...