Blar i Brage IMR på forfatter "Donald, Carey"
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Accumulation and toxicity of monoaromatic petroleum hydrocarbons in early life stages of cod and haddock
Sørensen, Lisbet; Hansen, Bjørn Henrik; Farkas, Julia; Donald, Carey; Robson, William; Tonkin, Andrew; Meier, Sonnich; Rowland, Steven J (Journal article; Peer reviewed, 2019)A multitude of recent studies have documented the detrimental effects of crude oil exposure on early life stages of fish, including larvae and embryos. While polycyclic aromatic hydrocarbons (PAHs), particularly alkyl PAHs, ... -
Alkyl-phenanthrenes in early life stage fish: differential toxicity in Atlantic haddock (Melanogrammus aeglefinus) embryos
Donald, Carey; Nakken, Charlotte L.; Sørhus, Elin; Perrichon, Prescilla; Jørgensen, Kåre Bredeli; Bjelland, Hege K.; Stølen, Christine; Kancherla, Sindhu; Mayer, Philipp; Meier, Sonnich (Peer reviewed; Journal article, 2023)Tricyclic polycyclic aromatic hydrocarbons (PAHs) are believed to be the primary toxic components of crude oil. Such compounds including phenanthrene are known to have direct effects on cardiac tissue, which lead to ... -
Alkyl-phenanthrenes in early life stage fish: differential toxicity in Atlantic haddock (Melanogrammus aeglefinus) embryos
Donald, Carey; Nakken, Charlotte L.; Sørhus, Elin; Perrichon, Prescilla; Jørgensen, Kåre Bredeli; Bjelland, Hege Kristoffersen; Stølen, Christine; Kancherla, Sindhu; Mayer, Philipp; Meier, Sonnich (Peer reviewed; Journal article, 2023)Tricyclic polycyclic aromatic hydrocarbons (PAHs) are believed to be the primary toxic components of crude oil. Such compounds including phenanthrene are known to have direct effects on cardiac tissue, which lead to ... -
Biological Responses of Pacific Herring Embryos to Crude Oil Are Quantifiable at Exposure Levels Below Conventional Limits of Quantitation for PAHs in Water and Tissues
Incardona, John P.; Linbo, Tiffany L.; Cameron, James R.; French, Barbara L.; Bolton, Jennie L.; Gregg, Jacob L.; Donald, Carey; Hershberger, Paul K.; Scholz, Nathaniel L. (Peer reviewed; Journal article, 2023)Pacific herring (Clupea pallasii), a cornerstone of marine food webs, generally spawn on marine macroalgae in shallow nearshore areas that are disproportionately at risk from oil spills. Herring embryos are also highly ... -
Cardiac dysfunction affects eye development and vision by reducing supply of lipids in fish
Sørhus, Elin; Meier, Sonnich; Donald, Carey; Furmanek, Tomasz; Edvardsen, Rolf Brudvik; Lie, Kai Kristoffer (Peer reviewed; Journal article, 2021)Developing organisms are especially vulnerable to environmental stressors. Crude oil exposure in early life stages of fish result in multiple functional and developmental defects, including cardiac dysfunction and abnormal ... -
Co-Exposure of Phenanthrene and the cyp-Inducer 3-Methylchrysene Leads to Altered Biotransformation and Increased Toxicity in Fish Egg and Larvae
Donald, Carey; Sørhus, Elin; Perrichon, Prescilla; Nakken, Charlotte L.; Goksøyr, Anders; Jørgensen, Kåre Bredeli; Mayer, Philipp; da Silva, Denis A.M.; Meier, Sonnich (Peer reviewed; Journal article, 2023)Polycyclic aromatic hydrocarbons (PAHs) have frequently been suspected of governing crude oil toxicity because of similar morphological defects in fish. However, PAH concentrations are often not high enough to explain the ... -
Co-exposure to UV radiation and crude oil increases acute embryotoxicity and sublethal malformations in the early life stages of Atlantic haddock (Melanogrammus aeglefinus)
Sørhus, Elin; Donald, Carey; Nakken, Charlotte L.; Perrichon, Prescilla; Durif, Caroline; Shema, Steven; Browman, Howard; Skiftesvik, Anne Berit; Lie, Kai Kristoffer; Rasinger, Josef; Müller, Mette Helen Bjørge; Meier, Sonnich (Peer reviewed; Journal article, 2023)Crude oil causes severe abnormalities in developing fish. Photomodification of constituents in crude oil increases its toxicity several fold. We report on the effect of crude oil, in combination with ultraviolet (UV) ... -
Crude oil exposure of early life stages of Atlantic haddock suggests threshold levels for developmental toxicity as low as 0.1 μg total polyaromatic hydrocarbon (TPAH)/L
Sørhus, Elin; Sørensen, Lisbet; Grøsvik, Bjørn Einar; Le Goff, Jérémie; Incardona, John P.; Linbo, Tiffany; Baldwin, David; Karlsen, Ørjan; Nordtug, Trond; Hansen, Bjørn Henrik; Thorsen, Anders; Donald, Carey; van der Meeren, Terje; Robson, William; Rowland, Steven J.; Rasinger, Josef; Vikebø, Frode Bendiksen; Meier, Sonnich (Peer reviewed; Journal article, 2023)Atlantic haddock (Melanogrammus aeglefinus) embryos bind dispersed crude oil droplets to the eggshell and are consequently highly susceptible to toxicity from spilled oil. We established thresholds for developmental toxicity ... -
Dietary beauvericin and enniatin B exposure cause different adverse health effects in farmed Atlantic salmon
Berntssen, Marc HG; Fjelldal, Per Gunnar; Gavaia, P.J.; Laizé, V.; Hamre, Kristin; Donald, Carey; Jakobsen, J.V.; Omdal, A.; Søderstrøm, Karin Sofie; Lie, Kai Kristoffer (Peer reviewed; Journal article, 2023)The extensive use of plant ingredients in novel aquafeeds have introduced mycotoxins to the farming of seafood. The emerging enniatin B (ENNB) and beauvericin (BEA) mycotoxins have been found in the novel aquafeeds and ... -
Differential developmental toxicity of crude oil in early life stages of Atlantic halibut (Hippoglossus hippoglossus)
Perrichon, Prescilla; Donald, Carey; Sørhus, Elin; Harboe, Torstein; Meier, Sonnich (Peer reviewed; Journal article, 2021)To further understand the complexity of developmental toxicity of dispersed oil and importance of exposure timing on fish early life stages, Atlantic halibut (Hippoglossus hippoglossus) were exposed to environmentally ... -
Discovery of polycyclic aromatic acid metabolites in fish exposed to the petroleum compounds 1-methylphenanthrene and 1,4-dimethylphenanthrene
Nakken, Charlotte Langeland; Meier, Sonnich; Mjøs, Svein Are; Bijlsma, Lubertus; Rowland, Steven J; Donald, Carey (Peer reviewed; Journal article, 2024)Most of the polycyclic aromatic hydrocarbons (PAHs) in petroleum are alkylated (alkyl PAHs), still the metabolism of these alkyl PAHs to the expected acid products (polycyclic aromatic acids; PAAs) has yet to be demonstrated ... -
Embryonic crude oil exposure impairs growth and lipid allocation in a keystone Arctic forage fish
Laurel, Benjamin J.; Copeman, Louise; Iseri, Paul; Spencer, Mari; Hutchinson, Greg; Nordtug, Trond; Donald, Carey; Meier, Sonnich; Allan, Sarah; Boyd, Daryle; Ylitalo, Gina; Cameron, James; French, Babara; Linbo, Tiffany; Scholz, Nathaniel; Incardona, John P. (Journal article; Peer reviewed, 2019)As Arctic ice recedes, future oil spills pose increasing risk to keystone species and the ecosystems they support. We show that Polar cod (Boreogadus saida), an energy-rich forage fish for marine mammals, seabirds, and ... -
Expression and localization of the aryl hydrocarbon receptors and cytochrome P450 1A during early development of Atlantic cod (Gadus morhua)
Aranguren Abadía, Libe; Donald, Carey; Eilertsen, Mariann; Gharbi, Naouel; Tronci, Valentina; Sørhus, Elin; Mayer, Philipp; Nilsen, Tom Ole; Meier, Sonnich; Goksøyr, Anders; Karlsen, Odd Andre (Peer reviewed; Journal article, 2020)The aryl hydrocarbon receptor (Ahr) is a ligand-activated transcription factor that mediates the toxicity of dioxins and dioxin-like compounds (DLCs) in vertebrates. Two clades of the Ahr family exist in teleosts (Ahr1 and ... -
Mind the gap – Relevant design for laboratory oil exposure of fish as informed by a numerical impact assessment model
Frøysa, Håvard Guldbrandsen; Nepstad, Raymond; Meier, Sonnich; Donald, Carey; Sørhus, Elin; Bockwoldt, Mathias; Carroll, JoLynn; Vikebø, Frode Bendiksen (Peer reviewed; Journal article, 2023)Laboratory experiments provide knowledge of species-specific effects thresholds that are used to parameterize impact assessment models of oil contamination on marine ecosystems. Such experiments typically place individuals ... -
Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua)
Aranguren Abadía, Libe; Yadetie, Fekadu; Donald, Carey; Sørhus, Elin; Myklatun, Lars Eirik; Zhang, Xiaokang; Lie, Kai Kristoffer; Perrichon, Prescilla; Nakken, Charlotte Langeland; Durif, Caroline; Shema, Steven; Browman, Howard; Skiftesvik, Anne Berit; Goksøyr, Anders; Meier, Sonnich; Karlsen, Odd André (Peer reviewed; Journal article, 2022)Photo-enhanced toxicity of crude oil is produced by exposure to ultraviolet (UV) radiation. Atlantic cod (Gadus morhua) embryos were exposed to crude oil with and without UV radiation (290–400 nm) from 3 days post fertilization ... -
Untangling mechanisms of crude oil toxicity: Linking gene expression, morphology and PAHs at two developmental stages in a cold-water fish
Sørhus, Elin; Donald, Carey; Da Silva, Denis; Thorsen, Anders; Karlsen, Ørjan; Meier, Sonnich (Peer reviewed; Journal article, 2020)