Browsing Brage IMR by Author "Bock, Christoph"

Now showing items 1-3 of 3

    • Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species 

      Klughammer, Johanna; Romanovskaia, Daria; Nemc, Amelie; Posautz, Annika; Seid, Charlotte A.; Schuster, Linda C.; Keinath, Melissa C.; Lugo Ramos, Juan Sebastian; Kosack, Lindsay; Evankow, Ann; Printz, Dieter; Kirchberger, Stefanie; Ergüner, Bekir; Datlinger, Paul; Fortelny, Nikolaus; Schmidl, Christian; Farlik, Matthias; Skjærven, Kaja Helvik; Bergthaler, Andreas; Liedvogel, Miriam; Thaller, Denise; Burger, Pamela A.; Hermann, Marcela; Distel, Martin; Distel, Daniel L.; Kübber-Heiss, Anna; Bock, Christoph (Peer reviewed; Journal article, 2023)
      Methylation of cytosines is a prototypic epigenetic modification of the DNA. It has been implicated in various regulatory mechanisms across the animal kingdom and particularly in vertebrates. We mapped DNA methylation in ...

    • One-carbon metabolism nutrients impact the interplay between DNA methylation and gene expression in liver, enhancing protein synthesis in Atlantic salmon 

      Saito, Takaya; Espe, Marit; Vikeså, Vibeke; Bock, Christoph; Thomsen, Tårn H.; Adam, Anne-Catrin; Fernandes, Jorge Manuel de Oliveira; Skjærven, Kaja Helvik (Peer reviewed; Journal article, 2024)
      Supplementation of one-carbon (1C) metabolism micronutrients, which include B-vitamins and methionine, is essential for the healthy growth and development of Atlantic salmon (Salmo salar). However, the recent shift towards ...

    • Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspring 

      Skjærven, Kaja Helvik; Jakt, Lars Martin; Fernandes, Jorge Manuel de Oliveira; Dahl, John Arne; Adam, Anne-Catrin; Klughammer, Johanna; Bock, Christoph; Espe, Marit (Journal article; Peer reviewed, 2018)
      Micronutrient status of parents can affect long term health of their progeny. Around 2 billion humans are affected by chronic micronutrient deficiency. In this study we use zebrafish as a model system to examine morphological, ...