Browsing Brage IMR by Author "Wargelius, Anna"
Now showing items 21-39 of 39
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MMP-13 (Matrix MetalloProteinase 13) expression might be an indicator for increased ECM remodeling and early signs of vertebral compression in farmed Atlantic salmon (Salmo salar L.)
Wargelius, Anna; Fjelldal, Per Gunnar; Grini, Ane; Gil-Martens, L.; Kvamme, Bjørn Olav; Hansen, Tom (Journal article; Peer reviewed, 2010-04)Vertebral body compression is a common problem in commercial farming of Atlantic salmon. Although risk factors, such as vaccination and alnutrition, have been identified, the etiology is largely unknown. Histological studies ... -
Oppdrett av steril fisk
Hansen, Tom; Wargelius, Anna; Taranger, Geir Lasse; Fjelldal, Per Gunnar (Rapport fra Havforskningen;Nr. 18 - 2012, Working paper, 2012-04)I andre land og andre arter er det vanlig å bruke triploidisering og/eller oppdrett av monosexbesetninger (f.eks all female). I noen andre arter er det dessuten vanlig å bruke sterile hybrider til ulike typer formål. ... -
Pituitary Gonadotropin Gene Expression During Induced Onset of Postsmolt Maturation in Male Atlantic Salmon: In Vivo and Tissue Culture Studies
Crespo, Diego; Skaftnesmo, Kai Ove; Kjærner-Semb, Erik Nordtorp; Yilmaz, Ozlem; Norberg, Birgitta; Olausson, Sara; Vogelsang, Petra; Bogerd, Jan; Kleppe, Lene; Edvardsen, Rolf Brudvik; Andersson, Eva; Wargelius, Anna; Hansen, Tom Johnny; Fjelldal, Per Gunnar; Schulz, Rüdiger W. (Peer reviewed; Journal article, 2022)Precocious male maturation causes reduced welfare and increased production costs in Atlantic salmon (Salmo salar) aquaculture. The pituitary produces and releases follicle-stimulating hormone (Fsh), the gonadotropin ... -
The Piwil1 N domain is required for germ cell survival in Atlantic salmon
Almeida, Fernanda Loureiro; Skaftnesmo, Kai Ove; Andersson, Eva; Kleppe, Lene; Edvardsen, Rolf Brudvik; Norberg, Birgitta; Fjelldal, Per Gunnar; Hansen, Tom Johnny; Schulz, Rüdiger W.; Wargelius, Anna (Peer reviewed; Journal article, 2022)Genetic introgression of farmed salmon into wild populations can damage the genetic integrity of wild stocks and is therefore considered as an environmental threat. One possible solution is to induce sterility in farmed ... -
Potential of genome editing to improve aquaculture breeding and production
Gratacap, Remi L.; Wargelius, Anna; Edvardsen, Rolf; Houston, Ross D. (Journal article; Peer reviewed, 2019)Aquaculture is an increasingly important component of global food security, and there is major potential for genetic improvement to contribute to sustainable production. The high fecundity and external fertilisation of ... -
Quantitative proteome profiling reveals molecular hallmarks of egg quality in Atlantic halibut: impairments of transcription and protein folding impede protein and energy homeostasis during early development
Yilmaz, Ozlem; Mangor-Jensen, Anders; Harboe, Torstein; Drønen, Margareth Møgster; Mangor-Jensen, Ragnfrid; Mjaavatten, Olav; Birkeland, Even; Spriet, Endy; Sandven, Linda; Furmanek, Tomasz; Berven, Frode Steingrimsen; Wargelius, Anna; Norberg, Birgitta (Peer reviewed; Journal article, 2022)Tandem mass tag spectrometry (TMT labeling-LC-MS/MS) was utilized to examine the global proteomes of Atlantic halibut eggs at the 1-cell-stage post fertilization. Comparisons were made between eggs judged to be of good ... -
Rescue of germ cells in dnd crispant embryos opens the possibility to produce inherited sterility in Atlantic salmon
Guralp, Hilal; Skaftnesmo, Kai Ove; Kjærner-Semb, Erik Nordtorp; Straume, Anne Hege; Kleppe, Lene; Schulz, Rüdiger W.; Edvardsen, Rolf Brudvik; Wargelius, Anna (Peer reviewed; Journal article, 2020)Genetic introgression of escaped farmed Atlantic salmon (Salmo salar) into wild populations is a major environmental concern for the salmon aquaculture industry. Using sterile fish in commercial aquaculture operations is, ... -
Sex steroid production associated with puberty is absent in germ cellfree salmon
Kleppe, Lene; Andersson, Eva; Skaftnesmo, Kai Ove; Edvardsen, Rolf; Fjelldal, Per Gunnar; Norberg, Birgitta; Bogerd, Jan; Schulz, Rüdiger W.; Wargelius, Anna (Peer reviewed; Journal article, 2017) -
Single nucleotide replacement in the Atlantic salmon genome using CRISPR/Cas9 and asymmetrical oligonucleotide donors
Straume, Anne Hege; Kjærner-Semb, Erik Nordtorp; Skaftnesmo, Kai Ove; Guralp, Hilal; Lillico, Simon; Wargelius, Anna; Edvardsen, Rolf Brudvik (Peer reviewed; Journal article, 2021)New breeding technologies (NBT) using CRISPR/Cas9-induced homology directed repair (HDR) has the potential to expedite genetic improvement in aquaculture. The long generation time in Atlantic salmon makes breeding an ... -
Stress and expression of cyclooxygenases (cox1, cox2a, cox2b) and intestinal eicosanoids, in Atlantic salmon, Salmo salar.
Olsen, Rolf Erik; Svardal, Asbjørn Martin; Eide, Torunn; Wargelius, Anna (Journal article; Peer reviewed, 2011-12-01)Prostaglandin H synthetases (cyclooxygenases) catalyze the initial reactions leading to prostanoids in animals. They form interesting links between diet and fish physiology as the type and nature of eicosanoids are affected ... -
Supplementary materials for Loss of Fshr prevents testicular maturation in Atlantic salmon (Salmo salar L.).
Andersson, Eva; Schulz, Rüdiger W; Almeida, Fernanda; Kleppe, Lene; Skaftesmo, Kai Ove; Kjærner-Semb, Erik; Crespo, Diego; Fjelldal, Per Gunnar; Hansen, Tom; Norberg, Birgitta; Edvardsen, Rolf B.; Wargelius, Anna (Others, 2024-01-30)Supplementary materials for "Loss of Fshr prevents testicular maturation in Atlantic salmon (Salmo salar L.)." published in Endocrinology, an Oxford academic journal https://doi.org/10.1210/endocr/bqae013 -
Sustained swimming increases the mineral content and osteocyte density of salmon vertebral bone
Totland, Geir K.; Fjelldal, Per Gunnar; Kryvi, Harald; Løkka, Guro; Wargelius, Anna; Sagstad, Anita; Hansen, Tom; Grotmol, Sindre (Journal article; Peer reviewed, 2011-05-25)This study addresses the effects of increased mechanical load on the vertebral bone of post-smolt Atlantic salmon by forcing them to swim at controlled speeds. The fish swam continuously in four circular tanks for 9 weeks, ... -
Targeted Mutagenesis in Atlantic Salmon (Salmo salar L.) Using the CRISPR/Cas9 System Induces Complete Knockout Individuals in the F0 Generation
Edvardsen, Rolf B.; Leininger, Svein; Kleppe, Lene; Skaftnesmo, Kai Ove; Wargelius, Anna (Journal article; Peer reviewed, 2014-09-25)Understanding the biological function behind key proteins is of great concern in Atlantic salmon, both due to a high commercial importance and an interesting life history. Until recently, functional studies in salmonids ... -
Targeted mutagenesis of Δ5 and Δ6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)
Jin, Yang; Datsomor, Alex Kojo; Olsen, Rolf Erik; Vik, Jon Olav; Torgersen, Jacob Seilø; Edvardsen, Rolf Brudvik; Wargelius, Anna; Winge, Per; Grammes, Fabian (Peer reviewed; Journal article, 2020) -
The influence of vgll3 genotypes on sea age at maturity is altered in farmed mowi strain Atlantic salmon
Ayllon, Fernando; Solberg, Monica Favnebøe; Glover, Kevin; Mohammadi, Faezeh; Kjærner-Semb, Erik Nordtorp; Fjelldal, Per Gunnar; Andersson, Eva; Hansen, Tom Johnny; Edvardsen, Rolf; Wargelius, Anna (Journal article; Peer reviewed, 2019)Background: In Atlantic salmon in the wild, age at maturity is strongly influenced by the vgll3 locus. Under farming conditions, light, temperature and feeding regimes are known significantly advance or delay age at ... -
The vgll3 Locus Controls Age at Maturity in Wild and Domesticated Atlantic Salmon(Salmo salar L.) Males
Ayllon, Fernando; Kjærner-Semb, Erik Nordtorp; Furmanek, Tomasz; Wennevik, Vidar; Solberg, Monica Favnebøe; Dahle, Geir; Taranger, Geir Lasse; Glover, Kevin; Sällman Almèn, Markus; Rubin, Carl J.; Edvardsen, Rolf; Wargelius, Anna (Journal article; Peer reviewed, 2015-11-09)Wild and domesticated Atlantic salmon males display large variation for sea age at sexual maturation, which varies between 1–5 years. Previous studies have uncovered a genetic predisposition for variation of age at maturity ... -
Transcriptome sequencing of Atlantic salmon (Salmo salar L.) notochord prior to development of the vertebrae provides clues to regulation of positional fate, chordoblast lineage and mineralisation
Wang, Shou; Furmanek, Tomasz; Kryvi, Harald; Krossøy, Christel; Totland, Geir Kåre; Grotmol, Sindre; Wargelius, Anna (Journal article; Peer reviewed; Peer reviewed, 2014) -
Transcriptome sequencing of Atlantic salmon (Salmo salar L.) notochord prior to development of the vertebrae provides clues to regulation of positional fate, chordoblast lineage and mineralisation
Wang, Shou; Furmanek, Tomasz; Kryvi, Harald; Krossoy, Christel; Totland, Geir K.; Grotmol, Sindre; Wargelius, Anna (Journal article; Peer reviewed, 2014-02-19)Background: In teleosts such as Atlantic salmon (Salmo salar L.), segmentation and subsequent mineralisation of the notochord during embryonic stages are essential for normal vertebrae formation. However, the molecular ... -
Vgll3 and the Hippo pathway are regulated in Sertoli cells upon entry and during puberty in Atlantic salmon testis
Kjærner-Semb, Erik Nordtorp; Ayllon, Fernando; Kleppe, Lene; Sørhus, Elin; Skaftnesmo, Kai Ove; Furmanek, Tomasz; Segafredo, Frida Thyri; Thorsen, Anders; Fjelldal, Per Gunnar; Hansen, Tom Johnny; Taranger, Geir Lasse; Andersson, Eva; Schulz, Rüdiger W.; Wargelius, Anna; Edvardsen, Rolf (Journal article; Peer reviewed, 2018)Vgll3 is linked to age at maturity in Atlantic salmon (Salmo salar). However, the molecular mechanisms involving Vgll3 in controlling timing of puberty as well as relevant tissue and cell types are currently unknown. Vgll3 ...